Fenugreek seed has been shown to affect the intestinal microbiota and immunological responses in animals. A feeding trial with male castrated piglets was performed over 28 d without or with the addition of 1·5 g fenugreek seeds/kg complete diet in ten and eleven piglets, weaned at 21 d. In the intestinal tract, pH, lactate and SCFA were measured as major bacterial metabolites. Immune cell pheno...

BACKGROUND Drugs used both in classical chemotherapy and the more recent targeted therapy do not have cancer cell specificity and, hence, cause severe systemic side effects. Tumors also develop resistance to such drugs due to heterogeneity of cell types and clonal selection. Several traditional dietary ingredients from plants, on the other hand, have been shown to act on multiple targets/pathwa...

Many traditional treatments have been recommended in the alterative system of medicine for the diabetes mellitus. Current research is now directed towards finding naturally occurring antidiabetic properties from plant origin. In Indian system of medicine Trigonella foenum graecum is an important medicinal plant and its leaves and seeds have been used in various ailments and as a health tonic. T...

Trigonella foenum-graecum (fenugreek) is an important medicinal plant, well known for its anti-inflammatory properties. However, the underlying cellular and molecular mechanisms of its action remain largely unknown. The apoptosis associated speck like protein containing a caspase recruitment domain (CARD) (ASC) is central to inflammatory and cell death pathways in innate and adaptive immunity. ...

fenugreek (trigonella foeum-graecum l.) has been used in iranian traditional medicine for treatment of different kinds of inflammation disorders. in the present study, anti- inflammatory activity of the methanolic extract of the plant (at doses of 100, 200 and 400 mg/kg) were studied using carrageenan-induced edema method and compared with the effects of dexamethasone and ibuprofen. various con...

Fenugreek is an medicinal plant that use in disease some therapy. This plant use  for blood lipids and sugar decreasing in diabetic and non diabetic peoples and have antioxidant and antibacterial activity. The plant contains active constituents such as alkaloids, flavonoids, steroids, Saponins etc. It is an old medicinal plant. It has been commonly used as a traditional food and medicine. Fenug...

The purpose of the study is to formulate and evaluate a new, cheap and effective natural mucoadhesive agent that can be used as an effective alternative for traditional mucoadhesive agent. The study procedure involved extraction of mucoadhesive agent from the Trigonellafoenumgraecum (fenugreek) seeds, solubility testing of the mucilage obtained, phytochemical testing, determination of swelling ...