We present a taxonomic revision of the crested newt Triturus karelinii sensu lato. Based on the presence of discrete nuclear DNA gene pools, deep genetic divergence of mitochondrial and nuclear DNA, and no indication of gene flow, we interpret this taxon as comprising two species: one covering the southern Caspian Sea shore, the Caucasus and the Crimea, i.e. the eastern part of the total range ...

OBJECTIVES We sought to demonstrate the long-term natural course of descending aorta dilation after acute aortic dissection (AD) and identify early predictors for late aneurysmal change. BACKGROUND Aneurysmal dilation of the aorta is a critical late complication in AD patients. METHODS Contrast-enhanced computed tomography (CT) was performed during the acute phase in 100 AD patients, compri...

BACKGROUND This study analyzed the relation between the tumor size and the lymph node metastasis in adenocarcinoma of the lung with a size of 30 mm or smaller. METHODS Four hundred thirteen patients who had undergone curative resection for lung adenocarcinoma were enrolled. If the tumor presented ground-glass opacities on the preoperative high-resolution computed tomography, both the total si...

BACKGROUND Chest compression quality is decisive for overall outcome after cardiac arrest. Chest compression depth may decrease when cardiopulmonary resuscitation (CPR) is performed on a mattress, and the use of a backboard does not necessarily improve compression depth. Mechanical chest compression devices may overcome this problem. OBJECTIVES We sought to investigate the effectiveness of ma...

Downlo PIM family of serine threonine protein kinases plays an important role in regulating both the growth and rmation of malignant cells. However, in a cell line–dependent manner, overexpression of PIM1 can t cell and tumor growth. In 22Rv1 human prostate cells, but not in Du145 or RWPE-2, PIM1 oversion was associated with marked increases in cellular senescence, as shown by changes in the le...

acrjourna h levels of the critical p53 inhibitor Mdm4 is common in tumors that retain a wild-type p53 allele, ting that Mdm4 overexpression is an important mechanism for p53 inactivation during tumorigenesis. t this hypothesis in vivo, we generated transgenic mice with widespread expression of Mdm4. Two ndent lines of transgenic mice, Mdm4 and Mdm4, developed spontaneous tumors, the most prevf ...

English teachers are frequently asked to help colleagues prepare presentations for internationalconferences. Sometimes this assistance takes the form of a language course or tutorials focusingon the spoken language. Contact time is short but the participants are highly motivated. Whattype of pronunciation work will provide the greatest payoff in terms of successfully beingunders...

Background and Objectives: Infection is the most common problem following burn injury. Selection and dissemination of intrinsic and acquired resistance mechanisms increase the probability of burn wound colonization by resistant species including Pseudomonas aeruginosa. Multi-drug resistant Pseudomonas ae...

GLM – General Linear Model Figure 2. Representative results from five patients. All panels: Top to bottom: mediolateral, coronal, craniocaudal sections; left:MR, right: DOT – beta values for the tumor model function. (a) 53 y, 33-mm IDC (model #1); (b) 77 y, 19-mm metaplastic CA (model #2); (c) 27 y, 22-mm fibroadenoma; (d) 37 y, 22-mm IDC; (e) 68 y, 16-mm IDC. 3 / 6 10 / 14 Sum 1 / 1 Melanoma ...