The age old paradigm of quantitative structure-activity relationship (QSAR) is the congenericity principle which states that similar structures usually have similar properties. But these days a lot of large and structurally diverse data sets of chemicals with the same experimental data (dependent variable) are available. Starting with the same classes of descriptors we extracted the two subsets...

3 4 Sandy M. S. Wong 1 , Frank St. Michael 3 , Andrew Cox 3 , Sanjay Ram 2 , and Brian J. Akerley 1 * 5 6 7 Department of Microbiology and Physiological Systems 1 and Division of Infectious Diseases and 8 Immunology 2 , University of Massachusetts Medical School, Worcester, MA, 01655, Institute for 9 Biological Sciences, National Research Council, Ottawa, ON Canada KIA 0R6 3 . 10 11 *Correspond...

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This study in Alexandria, Egypt was conducted to investigate the distribution of different hepatitis B virus (HBV) markers in apparently healthy blood donors who were hepatitis B surface antigen (HBsAg) negative, and to determine the major independent risk factors. Evidence of past exposure to HBV was found in 148/508 screened donors (29.1%). The most prevalent marker was anti-NBc in 124/508 do...