نتایج جستجو برای: 5 nitrofuran

تعداد نتایج: 1215932  

Journal: :Cancer research 2007
Maria Polycarpou-Schwarz Kerstin Müller Stefanie Denger Andrew Riddell Joe Lewis Frank Gannon George Reid

A series of nitrofuran-based compounds were identified as inhibitors of estrogen signaling in a cell-based, high-throughput screen of a diverse library of small molecules. These highly related compounds were subsequently found to inhibit topoisomerase II in vitro at concentrations similar to that required for the inhibition of estrogen signaling in cells. The most potent nitrofuran discovered i...

Journal: :Juntendo Medical Journal 1960

2016
Leyla Yurttaş Zafer Şahin Sevda Er Şeref Demirayak

INTRODUCTION The incidence of microbial infections have been increasing day by day in worldwide. Many antibacterial agents are in use against a wide range of infectious diseases1,2. However, the resistance to existing drugs is still a serious problem threat to global public health. This situation leads medicinal chemists to investigate newly synthesized more potent antimicrobial drugs3. Among m...

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