The bioactive glass 45S5 was crystallized to 8-100 vol % of crystals by thermal treatments from 550-680 degrees C. The micro-structure of the glass-ceramics had a very uniform crystal size, ranging from 8 to 20 microns. Fourier-transform infrared (FTIR) spectroscopy was used to determine the rate of hydroxycarbonate apatite (HCA) formation that occurs on bioactive glass and glass-ceramic implan...

Particulate 45S5 Bioglass with an average size of 46 microm was incorporated into a high density polyethylene (HDPE) for potential medical applications. Composites with Bioglass volumes of 10, 20, and 40% were produced by a manufacturing process consisting of blending, compounding, powdering, and compression molding. The Bioglass particles were well dispersed, and their homogeneous distribution...

The interfacial characteristics between bioactive glass (45S5 Bioglass) surfaces and poly(α-hydroxyacid) melts have been assessed by direct wetting measurements. In particular, the wettability of Bioglass powder by poly(D,Llactide) (PDLLA) and poly(D,L-lactide-co-glycolide) (PLGA) was assessed by imbibition measurements. Additionally, the equilibrium contact angles of PDLLA and PLGA melts on a ...

The key research and development steps for bioactive glass (45S5 Bioglass) are documented from the date of discovery in 1969 through FDA approvals of the first dental, ENT, maxillo-facial and orthopedic clinical products. Understanding the mechanisms and quantifying the rapid surface reactions to form a bone-bonding hydroxyl-carbonate apatite (HCA) layer on the bioactive glass in contact with l...

Silica-based and borate-based glass series, with increasing amounts of TiO₂ incorporated, are characterized in terms of their mechanical properties relevant to their use as metallic coating materials. It is observed that borate-based glasses exhibit CTE (Coefficient of Thermal Expansion) closer to the substrate's (Ti6Al4V) CTE, translating into higher mode I critical strain energy release rates...