Serum ferritin levels were estimated in 78 normal subjects (46 males and 37 females) using radioimmunoassay techniques. The mean serum ferritin level in normal men was 83 ng/ml (range 7.4 190.0 ng/ml), compared with 43 ng/ml (range 5.1 — 104 ng/mI) in normal women. The difference in the mean ferritin level between the two sexes was significant. A concentration below 10 ng/mI was associated with...

The effect of heat on 1,4-dihydroxy-5,8-bis[2-[(2-hydroxyethyl)amino]ethylamino]-9, 10-anthracenedione dihydrochloride (DHAD; mitoxantrone, NSC 301739) cytotoxicity was studied in V79 Chinese hamster cells. An overnight exposure to the drug at 40 degrees C enhanced drug damage in chromosome aberrations, culture growth, and cellular reproductive integrity. Preincubation of cells overnight in med...

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Recognition of self-antigens by T lymphocytes is a central event in autoimmunity. Understanding of the molecular interactions between T cell receptors (TCR) and self-epitopes may explain how T cells escape thymic education and initiate an autoimmune reaction. We have studied five human in vivo activated T cell clones specific for the region 535-551 of human thyroid peroxidase (TPO) established ...

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Direct communication between neighboring cells through connexin (Cx)-based gap junction is a crucial biolo-gical manner to regulate functions of a tissue consisting of multi-cell types. The present research evaluated expressional changes of Cx isoforms in the caput epididymis of adult rat exposed to estradiol benzoate (EB) or flutamide (Flu) at the early postnatal age. A single subcutaneous adm...

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introduction: colonoscopy is an invasive method that is painful for patient especially for children. the objective of this research was investigation of the effect of supermint oral drop (peppermint essence) on the patient and colonoscopist group satisfaction during colonoscopy.    materials and methods: one hundred and one patient's candidate for colonoscopy was randomly divided into two ...

Aims: To overcome contamination and temperature inhibition by isolating campylobacter at 37 C̊. Methods: The b lactam antibiotic aztreonam was included in a selective medium because of its inhibitory activity against Gram negative organisms but not against Campylobacter jejuni. Vancomycin and amphotericin were added to inhibit Gram positive bacteria and yeasts. Results: The aztreonam amphoterici...