نتایج جستجو برای: 420 and 97 m3s
تعداد نتایج: 16837932 فیلتر نتایج به سال:
Ligand affinity chromatography was used to purify a cell surface alpha 2-macroglobulin (alpha 2M) receptor. Detergent extracts of human placenta were applied to an affinity matrix consisting of alpha 2M, previously reacted with methylamine, coupled to Sepharose. Elution with EDTA specifically released polypeptides with apparent molecular masses of 420 and 39 kD. In some preparations, small amou...
Purpose: To study the role of drug transporters in central nervous system (CNS) penetration and cellular accumulation of erlotinib and its metabolite, OSI-420. Experimental Design: After oral erlotinib administration to wild-type and ATP-binding cassette (ABC) transporter-knockout mice (Mdr1a/b / , Abcg2 / , Mdr1a/b / Abcg2 / , and Abcc4 / ), plasma was collected and brain extracellular fluid (...
Mohammad H. Asghari and Bahram Jalali Department of Electrical Engineering, University of California, Los Angeles, 420 Westwood Plaza, Los Angeles, California 90095, USA Department of Bioengineering, University of California, Los Angeles, 420 Westwood Plaza, Los Angeles, California 90095, USA Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, 420 West...
DNA/RNA Description DNA contains 27.322 kb composed of 20 coding exons. Exons 1-2 encode the 5' untranslated region and the signal peptide, exons 3-7 the five EGF domains, exons 8-13 the extracellular stalk, exons 14-18 the seven-span transmembrane (TM7) domains and exons 19-20 the intracellular part and the 3' untranslated region. Transcription 3247 bp mRNA transcribed in telomeric to centrome...
M. Hanzelka, J. Dan, M. Šlepecky, V. Holcner, P. Dohnal, R. Kadlec 1Department of Theoretical and Experimental Electrical Engineering, Brno University of Technology, Technická 3082/12, 616 00 Brno, Czech Republic [email protected], tel.: +420 54114 6280, fax: +420 5 4114 6276 2Rector’s Office, Personnel Management Office, Masaryk University, Žerotínovonám. 9, 601 77 Brno, Czech Republic da...
Treatment resistant depression can be very disabling and has a significant negative impact on patient, their family or caregivers, the society. There is growing evidence efficacy safety of ketamine for treatment depression. Ketamine racemate consisting esketamine arketamine, an N-methyl D-aspartate receptor antagonist comes in different formulations fact intranasal FDA-approved US. Despite exis...
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