نتایج جستجو برای: 4 tetrazole

تعداد نتایج: 1304086  

Journal: :Chemical communications 2008
Yue-Ling Bai Jun Tao Rong-Bin Huang Lan-Sun Zheng Shao-Liang Zheng Kazuyoshi Oshida Yasuaki Einaga

A three-dimensional mixed-valence iron complex with NiAs-type topology, [(Fe(III)(3)O)Fe(II)(TA)(6)(H(2)O)(3)].(ClO(4))(2)(NO(3))(EtOH)(H(2)O)(2) (1, HTA = tetrazole-1H-acetic acid), shows spin-crossover behavior that was characterized via variable-temperature crystal structures, Mössbauer spectra and magnetic susceptibilities, the pressure effects on the transition behavior were also studied.

2010
V. H. BHASKAR P. B. MOHITE MP Patel

In attempt to find new pharmacologically active molecules, we report here the synthesis and in vitro anti-inflammatory activity of various 1-[5-(substituted phenyl)-1-phenyl-4,5dihydro-1H-pyrazol-3-yl]-5-phenyl-1H-tetrazole (IV a-h).The anti-inflammatory activity of title compounds were examined by denaturation of proteins method. All the compounds exhibited weak to potent anti-inflammatory act...

Journal: :Angewandte Chemie 2008
Wenjiao Song Yizhong Wang Jun Qu Michael M Madden Qing Lin

2010
V. H. BHASKAR P. B. MOHITE

Different tetrazole derivatives containing isoxazole has been synthesized. 5-phenyl tetrazoles (1) was cyclized using sodium azide and ammonium chloride and benzonitrile. The 5-phenyl tetrazoles on treatment with acetic anhydride forms 5-phenyl 1-acetyl Tetrazole (2) which on reaction with different aromatic aldehydes forms chalcones (3ah).The chalcones further undergo cyclisation with hydroxyl...

Tetrazole-containing compounds have been the subject of much recent research because of theirpotential as high energy density materials (HEDMs). In this work, theoretical studies on the 1Htetrazolylderivatives of tetrahedrane were done at the density functional theory (DFT) method withthe 6-31G(d) basis set without any symmetrical restrictions in order to find the structural andenergetically pr...

Journal: :Acta Crystallographica Section E Structure Reports Online 2010

Journal: : 2023

This work involved the synthesis of tetrazole derivatives 4,4'-(((sulfonylbis(4,1-phenylene))bis(diazene-2,1-dil))bis(2-(1-(4-R)phenyl]-4),5-Dihydro-1H-tetrazol-5-yl(phenol) (where R = OH or OCH3) through reaction substituted amine in THF as a solvent, with sodium azide. FT-IR 1H-NMR Spectrophotometric methods were used to characterize prepared compounds, antibacterial activity against four typ...

Journal: :Bioorganic & medicinal chemistry letters 2011
Thomas E Barta Daniel P Becker Louis J Bedell Alan M Easton Susan L Hockerman James Kiefer Grace E Munie Karl J Mathis Madeleine H Li Joseph G Rico Clara I Villamil Jennifer M Williams

Seeking compounds preferentially potent and selective for MMP-13, we reported in the preceding Letter on a series of hydroxamic acids with a flexible benzamide tail groups.(1a) Here, we replace the amide moiety with non-hydrolyzable heterocycles in an effort to improve half-life. We identify a hydroxamate tetrazole 4e that spares MMP-1 and -14, shows >400-fold selectivity versus MMP-8 and >600-...

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