Objective(s): To investigate the effects of Nonylphenol (NP) in pups from dams exposed during gestational and lactational periods on immediate early genes (c-jun, c-fos) in hippocampus and the learning and memory of F1 rats. Materials and Methods: Twenty eight pregnant dams, stratified by pregnancy date, were randomly assigned into 4 groups, which were gavaged with NP at the doses of 50 mg/kg/d...

We consider variations on the classic video game Tetris where pieces are k-ominoes instead of the usual tetrominoes (k = 4), as popularized by the video games ntris and Pentris. We prove that it is NP-complete to survive or clear a given initial board with a given sequence of pieces for each k ≥ 5, complementing the previous NP-completeness result for k = 4. More surprisingly, we show that boar...

Background: Influenza vaccines based on conserved proteins are being developed persistently. The conserved protein vaccines based on Nucleoprotein (NP) are highly protected vaccines against influenza viruses that can be used as a Universal vaccine. Aluminum hydroxide (Alum) is the most common adjuvant used in vaccine formulation to improve immunization by altering the epitopes’ folds. However, ...

Huntington's disease (HD) is an autosomal dominant neurodegenerative disease. Accordingly, 3-nitropropionic acid (3-NP) has been found to effectively produce HD-like symptoms. Luehea divaricata (L. divaricata), popularly known in Brazil as "açoita-cavalo," may act as a neuroprotective agent in vitro and in vivo. We evaluated the hypothesis that the aqueous extract of L. divaricata could prevent...

background and aims. in contrast to prepared natural dentin abutments, little is known concerning factors influencing the retention of fixed prostheses cemented to implant abutments. the aim of this study was to investigate the effect of implant abutment height on the retention of single castings cemented to wide and narrow platform implant abutments. materials and methods. thirty-six parallel-...

The immunoperoxidase localization of carcinoembryonic antigen (CEA) determinants was studied in colonic adenocarcinomas using four murine monoclonal antibodies to CEA in a bridged avidin:biotin technique. One of the monoclonal antibodies, NP-1, recognizes a CEA epitope shared with the nonspecific cross-reacting antigen and meconium antigen. Two others, NP-2 and NP-3, discriminate two separate C...

This work intended to enhance the unique and outstanding properties of lanthanum by synthesizing its nanocomposite. A lanthanum-based nanocomposite was prepared a simple cost-effective “co-precipitation” method. Lanthanum nitrate (La (NO3)3) zinc (Zn (NO3)2) were used as precursors. The lanthanum/zinc oxide nano composite formed then calcined at 450 °C for 4 h in order obtain fine powder with s...