There have been no reports of serious adverse reactions with the use of topical ivermectin in a limited number of patients (i.e., fewer than 400).1,2 Ivermectin 0.5% lotion does not have the neurotoxicity concerns of lindane or the flammability concerns of malathion (Ovide).2,3 The safety of the lotion has not been established in patients younger than six months, and use in this age group is no...

Under chloroform the intestines were washed with warm boric lotion and carefully put back into the abdominal cavity. There were a few small splinters of wood found in the su1 perficial wound, which were carefully removed, | and the wound washed clean with warm boric lotion The peritoneum was sutured with aseptic catgut and skin with horse-hair ; thoroughly dusted with iodoform and dressed. Opiu...

Two U.S. military issue deet repellent formulations (75% deet liquid and 33% deet lotion) and Avon Skin-So-Soft were tested against ceratopogonid midges under field conditions in Honduras. Test subjects were U.S. military personnel deployed to Honduras for training. Culicoides furens accounted for 96.3% of all midges collected. The liquid and lotion formulations of deet and Avon Skin-So-Soft pr...

BACKGROUND Moisturizers with anti-inflammatory or anti-itch activity should be developed for the safe and effective management of atopic dermatitis (AD). OBJECTIVE This study evaluated the efficacy of a newly developed moisturizer, CSP0510 lotion (Twolines Inc., Korea), containing citric acid (CA) and trisodium phosphate (TSP) as active ingredients, in mild to moderate AD. METHODS AND RESUL...

In this investigation of effectiveness of an alternative pediculicide dosage form, we recruited 228 children and 50 adult participants from Bedfordshire, UK, to a randomised, controlled, assessor blind trial comparing two insecticide products with mechanical removal of lice as a control group.  Participants using insecticide were treated with either the investigative 0.5% phenothrin mousse, for...

Back Cover: In article number 2100712 by Ivan Ivanov and co-workers, a functionalized dimethicone, commercially used as emulsifier in cosmetics, self-assembles into vesicles even provides suitable environment for membrane proteins. Upon vigorous agitation the presence of physiological concentrations salt, these continuously fuse to reach micrometer dimensions, taking up biopolymers nucleotides ...

Abstract Background We describe a “stability-indicating liquid chromatography” technique for the estimation of dimethicone (DEC) and dicyclomine hydrochloride (DEH) in established tablet formulations. Individual quantification DEH DEC was reported. But simultaneous lacking. were analysed on an “XTerra C 18 column (250 mm × 4.6 mm, 5 μm)” with mobile phase solvent run isocratically 0.1M K 2 HPO ...

background:  scabies is an ectoparasitic infection, which occurs because of direct skin-to skin contact. the ideal treatment modality is still unclear and further research on this topic is warranted. the aim of the study was to com­pare the efficacy and safety of the topical scabicides: permethrin, crotamiton and sulfur ointment. methods: fifty four patients with diagnosed scabies were randomly...

Understanding the interactions of nanoparticles (NPs) with skin is important from a consumer and occupational health and safety perspective, as well as for the design of effective NP-based transdermal therapeutics. Despite intense efforts to elucidate the conditions that permit NP penetration, there remains a lack of translatable results from animal models to human skin. The objectives of this ...

Best practice care for prevention and treatment of Incontinence Associated Dermatitis (IAD) includes use of a moisture barrier cream, ointment, or film. However, it has been suggested that some barrier products, particularly those that are petrolatum-based, may interfere with brief absorption. The objective of the study was to test the hypothesis that a unique polymer-based barrier cream has le...