نتایج جستجو برای: 4 dihydroquinoline
تعداد نتایج: 1303673 فیلتر نتایج به سال:
Hydride transfer from N,N, 1,2,4-pentamethyl-1,4-dihydronicotinamide, 1, to methyl 2-methoxycarbonylimino-phenylacetate, 3, was accomplished in an optical yield 2 95 %. Efficient chirality transfer from reduced NADH models to prochiral carbonyl substrates has i.a. been achieved with pentamethylated 1,4-dihydronicotinamide 1. ’ In comparison with 1,4-dihydroquinoline analogues,’ NADH model 1 is ...
RuNPs stabilised by amino-decorated imidazolium-based polymer immobilized ionic liquids catalyse the dimethylamine borane mediated reduction of quinolines to 1,2-dihydroquinoline (DHQ) and 1,2,3,4-tetrahydroquinoline (THQ). Partial 3-substituted corresponding was achieved with 100% selectivity in toluene under mild conditions. This is first report selective partial 1,2-dihydroquinolines a heter...
A multi-gram scale protocol for the N-acyl amidation of bile acids with glycine and taurine has been successfully developed under continuous flow processing conditions. Selecting ursodeoxycholic acid (UDCA) as the model compound and N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) as the condensing agent, a modular mesoreactor assisted flow set-up was employed to significantly speed up the...
The aim of the work. Among all representatives four generations fluoroquinolones ciprofloxacin (CIPRO) and norfloxacin (NOR) remain widely used prescribed antibiotics in clinical practice. However, problem resistance towards them is gradually increasing. Thus, our investigation dedicated to chemical modification C-7 position Ciprofloxacin Norfloxacin ring as a promising solution combat antibiot...
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