Optically pure â,â-dimethylated amino acid building blocks with functionalized side chains have been prepared from D-aspartic acid. The dimethylation was accomplished by regioselective dialkylation of 9-phenylfluorenyl (PhFl)-protected aspartate diesters. The bulk of the PhFl protecting group also allowed for a variety of functional group manipulations to be carried out on the side chain withou...

Sialic acid has been shown to contribute significantly to the cell-surface charge of tumor cells. In order to elucidate the chemical nature of the sialic acid-containing molecules present on the tumor cell surface, a procedure for the isolation of a Sialoglycopeptide fraction from the surface of Novikoff ascites cells has been developed. Digestion of tumor cell suspensions with papain liberates...

Š + Z s x Z v ¬ \ » W y ~ x ì 7 g ~ ¬ Ý Z K̈ +M Å @ Z e$ Ô Z & b z # b Z z g ] Æ n W c* ì X Z s x Z q§ ] 6, z g Š + ì ) 1 ( å Ÿ $ î E 0 § ] Z z g Z qY ì Š 2 g ) 2 ( ì X Z v ¬ \ ä Ñ < * i w Û â ð ì Z k ~ t & ¢A g ¿ ì z { CÙ q w ~ Š * Å g É ð TM n Ô Z z g CÙ 2 w ~ p | ] · Z v m z Å Z v ¬ \ Æ W y ~ g Î w X Æ Š Z ], { t ] Ã 5+ k, Z K̈ +M » ‚ B Š } n Z z g CÙ i â y z k y 6, ” Z z g Z $+ Z Ñ !...

MAT-B1 and M A I -( 1 ascites subîmes of the 13762 rat mammary adenocarcinoma both contain sialomucin as a major cell surface compo nent and are resistant to cytolysis by normal rat spleen lymphocytes |3 ±2% (SD) and O ±1%, respectively). Susceptibility to lysis did not increase following treatment of cells with neuraminidase, fucosidase, or aor 0-galactosidase. Treatment with trypsin signif...

Following [Akizuki], I construct a Noetherian local integral domain CM whose normalisation (integral closure) is not finite over CM . My proof follows closely Akizuki’s ingenious calculations. Let A be a DVR with local parameter t and residue field k = A/(t), and  the completion of A. There are no restrictions on the characteristic of A or k, but I assume that  contains a transcendental eleme...

f × ß r o 0 9 8 1 Y ( ä /| 2 3 8 1 Y X 7 0 3 1 /| Z g Š z Š * ñ D ~ â Z [ ¦ œ & Œ ¦ Y È 0* à ò ) 8 4 2 1 Z z g Z y Å Â [ § ] » ̧ ] ƒ Ð ¬ ¬ g s TM Z c* X â Z [ ñ ß s ò ä § ] ó g Å § ] z q Ñ ] Æ !* g } ~  1⁄4 7 – Ô Ü s Z y Æ * x * ò Z z g Z y Æ Ä Ð Z y Æ !* g } ~ É TM Z y Å Â [ § ] » ¿ c z s ® ð g ¶ Z v ¬ \ ä  [ â g Z Ñ w g ~ &+ TM § ] t t 1⁄4 – ì f × ß r o f TM H ì : L L Z â x ¦ Z z k Ð 3 _...

N. Marõ  n, Dpto. de Dida  ctica de la Matematica y de las Ciencias Experimentales, Facultad de Ciencias de la Educacio  n, Universidad de Almerõ  a, Spain A. Benarroch, Dpto. de Dida  ctica de las Ciencias Experimentales, Escuela de Magisterio de Melilla, Universidad de Granada, Spain E. Jime  nez Go  mez, Dpto. de Dida  ctica de las Ciencias Experimentales, Facultad de Educacio  n, U...

The quantum phase description of Noh, Fougères and Mandel (NFM) leads to a two-mode theory of phase in the strong local oscillator limit. We show that the explicit form of the eigenstates of the sine and the cosine phase operators in two-mode Fock space can be constructed. This brings great convenience to the NFM quantum phase approach. Recently, phase operators and phase measurements in quantu...

classes in N(p,q). We show that X(p,q) with the quotient topology is homeomorphic to the compact, connected quotient space G(p, so(q,Â)) / SL(q,Â), where SL(q,Â) acts on so(q,Â) and the associated Grassmann manifold G(p, so(q,Â)) by g(Z) = gZgt for Z ∈ so(q,Â) and g ∈ SL(q,Â). It follows immediately that X(p,q) is homeomorphic to X(D−p,q), where D = dim so(q,Â) = (1/2)q(q−1) (duality). For each...