BACKGROUND Loop diuretics are widely used in patients with heart and renal failure, as well as to treat hypertension and peripheral edema. However, there are no randomized, controlled trials (RCT) evaluating their long term safety, and several observational reports have indicated adverse effects. We sought to evaluate the impact of loop diuretics on long term survival in patients with suspected...

We retrospectively analyzed 1062 respiratory specimens from 214 patients with cystic fibrosis, of whom 5 patients had 36 cultures positive for M. abscessus. Results of molecular typing demonstrated that each of these 5 patients carried a single unique strain (genotype), which suggests that it may not be necessary to segregate patients with CF who are colonized or infected with M. abscessus from...

In this issue of Genes & Development, Siebert and colleagues (pp. 1052-1062) define a ligand-receptor system that controls motor axon guidance and target recognition in the Drosophila embryo. The beaten path (beat) and sidestep (side) genes were known to be important regulators of motor axon guidance. Siebert and colleagues now show that Beat and Side are cell surface proteins that physically i...

PT Petrokimia Gresik merupakan salah satu perusahaan pupuk terbesar yang ada di Indonesia. Selain menghasilkan pupuk, juga produk non-pupuk satunya yaitu AlF3 (Aluminium Fluorida) memiliki kapasitas produksi 12.600 ton/tahun. Bahan baku digunakan adalah H2SiF6 (Asam Fluosilikat) serta Al(OH)3 Hidroksida). Dalam pembuatannya, perlu dipanaskan terlebih dahulu menggunakan heater (E-3101) hingga su...

A. Zobelli,1,2,* A. Gloter,1 C. P. Ewels,3 and C. Colliex1 1Laboratoire de Physique des Solides, Université Paris-Sud, CNRS, UMR 8502, F-91405 Orsay Cedex, France 2Technische Universität Dresden, Institüt für Physikalische Chemie und Elektrochemie, D-1062 Dresden, Germany 3Université de Nantes, Nantes Atlantique Universités, CNRS, Institut des Matériaux Jean Rouxel (IMN), UMR6502, BP32229, F-44...

Abstract Background and Aims Patients with end stage renal disease (ESKD) on hemodialysis (HD) have a high risk of cardiovascular (CV) events, this being mostly related to the presence uraemic cardiomyopathy. A deregulation in expression various microRNAs (miRNAs: non-coding RNAs that regulate post-transcriptional gene expression) has previously been implied pathological cardiac remodelling. Ne...