INTRODUCTION We aimed to quantify a relationship between radiotherapy dose and freedom from biochemical failure (FFBF) in low- and intermediate-risk prostate cancer. To reduce confounding we used data with a standardised end-point, mature follow-up, low competing risk of metastatic failure, conventional fractionation and separate reporting for outcomes with hormonal therapy (HT). METHODS A sy...

PURPOSE To measure the optic disc rotation around the vertical and horizontal disc axis and to evaluate associations with general and ocular parameters. DESIGN Population-based study. METHODS In the Beijing Eye Study, 3468 participants (mean age:64.6±9.8 years; range:50-93 years) underwent an ophthalmological examination which included spectral-domain optical coherence tomography (OCT) with...

______________________________________________________________________________________________ Background: Jute industry workers constantly exposed themselves to jute dust and are at risk of impairment of lung function. Investigation on various studies revealed the effects of exposure to jute dust but limited studies so far undertaken regarding its bearing on pulmonary function of jute workers ...

Network research often involves the evaluation of new application designs, system architectures, and protocol implementations. Due to the immense scale of the Internet, deploying an Internet-wide system for the purpose of experimental study is nearly impossible. Instead, researchers evaluate their designs using generated random network topologies. In this report, we present a topology generator...

Oliveira M.S., Muzzi R.A.L., Muzzi L.A.L., Cherem M. & Mantovani M.M. 2014. QT interval in healthy dogs: which method of correcting the QT interval in dogs is most appropriate for use in small animal clinics? Pesquisa Veterinária Brasileira 34(5):469472. Departamento de Medicina Veterinária, Universidade Federal de Lavras, Cx. Postal 3037, Lavras, MG 37200-000, Brazil. E-mail: [email protected]...

This chapter presents a memetic framework for solving the Synchronized and Integrated Two-level Lot Sizing and Scheduling Problem (SITLSP). A set of algorithms from this framework is thoroughly evaluated. The SITLSP is a real-world problem typically found in soft drink plants, but its presence can also be seen in many other multi-level production processes. The SITLSP involves a two-level produ...

INTRODUCTION Plasma levels of cell-free hemoglobin are associated with mortality in patients with sepsis; however descriptions of independent associations with free hemoglobin and free heme scavengers, haptoglobin and hemopexin, are lacking beyond their description as acute phase reactants. We sought to determine the association of plasma levels of endogenous free hemoglobin and haptoglobin and...

RATIONALE Kawasaki disease (KD), an acute febrile vasculitis, is the most common cause of acquired heart disease in childhood; however, diagnosing KD can be difficult. OBJECTIVE To identify unique proteomic biomarkers that can be used to facilitate earlier diagnosis of KD. METHODS AND RESULTS We enrolled 214 children with fever and clinical features suggestive of KD. Of those, only 100 were...

Software modeling is an important activity for maintenance since it can facilitate the software comprehension as well as the understanding of its activities towards evolution, correction and adaptation. In this sense, maintainability and its subcharacteristics as presented in the ISO/IEC 9126 standard should be incorporated to the artifacts produced in the modeling activity aiming at designing ...

BACKGROUND Inflammation (assessed by C-reactive protein [CRP]) and the metabolic syndrome (MetS) are associated with cardiovascular disease (CVD), but population-based data are limited. METHODS AND RESULTS We assessed the cross-sectional relations of CRP to the MetS (National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults...