In recent years there has been a surge in methylphenidate (Ritalin) use for treatment of attention deficit/hyperactivity disorder (ADHD) in children. However, there is a paucity of information on whether this drug poses any potential health risks, such as mutagenicity or carcinogenicity, for humans. To address this issue, we investigated whether this central nervous system stimulant produces cy...

background: the main part of ovary is consisted of follicles which certain drugs may cause change in them. objectives: the purpose of this study was to investigate the effects of methylphenidate on ovarian follicle of mice, treated by ritalin before puberty. methods: 40 immature female mice at 3 weeks of age were divided into 4 groups, consisting of one control and 3 experimental groups. the ex...

OBJECTIVE To determine the impact of immediate release Ritalin, given three times a day, on sleep quality and quantity in medication-naïve, newly diagnosed children with attention-deficit/hyperactivity disorder (ADHD). METHODS Children (aged 6-12) rigorously diagnosed with ADHD (n = 21) underwent multiple measurement assessments (i.e., actigraphy, sleep diary, and questionnaires) during a 1-w...

Attention Deficit Hyperactivity Disorder (ADHD) has become a hallmark disorder of American society, especially among children. The Center for Disease Control estimates seven percent of the school-age population has the disorder and numerous studies have shown that the number of children, adolescents and now adults who are treated with medication for the disorder continues to increase. It has be...

Talcosis due to intravenous injection of oral drugs can cause severe pulmonary disease with progressive dyspnea even when drug use is discontinued. We describe a 54-year-old woman with severe emphysema who underwent left lung transplantation. The patient had a remote history of intravenous injection of crushed methylphenidate (Ritalin) tablets. Chest computed tomography showed severe emphysemat...