Group B streptococci (GBS; Streptococcus agalactiae) are the leading cause of neonatal invasive diseases and are also important pathogens for adults. Penicillins are the drugs of first choice for the treatment of GBS infections, since GBS have been regarded to be uniformly susceptible to penicillins so far. Here we characterize the first strains of GBS with reduced penicillin susceptibility (PR...

We have previously reported the identification of a distinct myosin heavy chain (MyHC) isoform in a major subpopulation of rat skeletal muscle fibers, referred to as 2X fibers (Schiaffino, S., L. Gorza, S. Sartore, L. Saggin, M. Vianello, K. Gundersen, and T. Lømo. 1989. J. Muscle Res. Cell Motil. 10:197-205). However, it was not known whether 2X-MyHC is the product of posttranslational modific...

This study was aimed to achieve a definitive and unambiguous identification of fiber types in canine skeletal muscles and of myosin isoforms that are expressed therein. Correspondence of canine myosin isoforms with orthologs in other species as assessed by base sequence comparison was the basis for primer preparation and for expression analysis with RT-PCR. Expression was confirmed at protein l...

PURPOSE Osseointegrated implants lack a periodontal ligament. Nevertheless, masticatory function in subjects with implant-supported restorations appears similar to function in those with natural dentition. It is not clear how the neurophysiologic mechanisms that modulate jaw movement are associated with osseointegrated implants. This study examined the output from the inferior alveolar nerve du...

Zygotically contributed ovo gene product is required for the survival of female germ cells in Drosophila melanogaster. Trans-allelic combinations of weak and dominant ovo mutations (ovoD) result in viable germ cells that appear to be partially transformed from female to male sexual identity. The O V O ” ~ mutation is partially suppressed by many Sex-lethal alleles that affect the soma, while th...

and Applied Analysis 3 is called a quadratic functional equation. In particular, every solution of the quadratic functional equation is said to be a quadratic mapping. A generalized Hyers-Ulam stability problem for the quadratic functional equation was proved by Skof 7 for mappings f : X → Y , where X is a normed space and Y is a Banach space. Cholewa 8 noticed that the theorem of Skof is still...

and Applied Analysis 3 2. Solution of 1.5 , 1.6 Let X and Y be real vector spaces. We here present the general solution of 1.5 , 1.6 . Theorem 2.1. A function f : X → Y satisfies the functional equation 1.3 if and only if f : X → Y satisfies the functional equation 1.5 . Therefore, every solution of functional equation 1.5 is also a quadratic function. Proof. Let f satisfy the functional equati...