Abstract Background Residing in areas of low socioeconomic advantage is associated with increased risk dementia 1 and brain pathology 2,3 . Given the long insidious course pathologies, it critical to establish effect ‘exposomic’ factors midlife understand which groups people are particularly vulnerable. Therefore, objective this study was examine whether cognitive performance or differed accord...

The present study was undertaken to examine whether the beta adrenergic agonist, isoproterenol, increases plasma renin activity (PRA) by activation of intrarenal or extrarenal pathways. The effects of intravenous (i.v.) and renal arterial infusion of isoproterenol on PRA and renin secretion rate (RSR) were compared in anesthetized dogs. In 12 studies in 9 dogs i.v. infusion of isoproterenol (0....

1. American Diabetes Association. Diabetes Care. 2014;37(Suppl 1):S14-S80. 2. Department of Health and Children. Changing Cardiovascular Health: National Cardiovascular Health Policy, 2010-2019. Dublin, Ireland: Department of Health and Children; 2010. http://www.dohc.ie/publications/pdf/changing_cardiovascular_ health.pdf. Accessed 3 Oct 2014. 3. Canavan R. Presented at: National Association o...

BACKGROUND Emerging interventions that rely on and harness variability in behavior to adapt to individual performance over time may outperform interventions that prescribe static goals (e.g., 10,000 steps/day). The purpose of this factorial trial was to compare adaptive vs. static goal setting and immediate vs. delayed, non-contingent financial rewards for increasing free-living physical activi...

Herpesvirus glycoproteins play dominant roles in the initiation of infection of target cells in culture and thus may also influence viral tropism in vivo. Whereas the relative contribution of several nonessential glycoproteins to neurovirulence and neurotropism of Pseudorabies virus (PrV), an alphaherpesvirus which causes Aujeszky's disease in pigs, has recently been uncovered in studies using ...

Abstract Study question What are the neonatal outcomes of fresh/frozen-thawed embryos derived from monopronuclear zygotes (1PN)? Is there any influence method fertilization? Summary answer A total 231 monoembryonic transfers (TF) fresh or frozen/thawed 1PN allows to birth twenty-seven healthy babies. is known already Zygotes were classified 16 18 hours post insemination according extrusion seco...

It has been more than six decades since the first report of sickle cell anaemia in Indian subcontinent. Since then the researchers have been reported various haemoglobin varients prevalent in India, they are HbS, Hbβ(T), HbE and HbD. Earlier studies were confined to tribal and scheduled castes populations as if sickle haemoglobin was restricted to these two groups only. Since a decade or so, fe...

BACKGROUND Edentulism is an important issue and will remain so due to high numbers of edentate individuals worldwide. For many years, complete dentures have been the only treatment option for this population. Implant overdentures have been shown to have many advantages over conventional complete dentures. However, although dissatisfied with their mandibular dentures, some edentate elders are re...

Patients with pulmonary alveolar proteinosis (PAP) display impaired surfactant clearance, foamy, lipidfilled alveolar macrophages, and increased cholesterol metabolites within the lung. Neutralizing autoantibodies to granulocyte-macrophage colony-stimulating factor (GMCSF) are also present, resulting in virtual GM-CSF deficiency. We investigated ABCG1 and ABCA1 expression in alveolar macrophage...

BACKGROUND The risk of hepatocellular carcinoma (HCC) increases with increasing level of hepatitis B virus (HBV) in serum (viral load). However, it is unclear whether genetic characteristics of HBV, including HBV genotype and specific genetic mutations, contribute to the risk of HCC. We examined the HCC risk associated with HBV genotypes and common variants in the precore and basal core promote...