Abstract Objectives To describe and review a series of penile trauma. Methods Patients with suspicions fracture that received surgical treatment were included from 2015 to 2022. Characteristics collected: date birth, type affected parts the penis, evolution after surgery. Description complications outcomes. Results 11 consecutive patients due suspicion 3 had negative previous ultrasonography. s...

Introduction Emergency psychiatric consultation requests present certain specificities both in the situations encountered and their management, due to a close relationship between consultant his environment. They do not only correspond emergencies, strict sense of term, but also psychological emergencies with possible social dimension. require an adapted response that can be decisive for future...

We conducted a large-scale association study to identify low-penetrance susceptibility alleles for chronic lymphocytic leukemia (CLL), analyzing 992 patients and 2707 healthy controls. To increase the likelihood of identifying disease-causing alleles we genotyped 1467 coding nonsynonymous single nucleotide polymorphisms (nsSNPs) in 865 candidate cancer genes, biasing nsSNP selection toward thos...

AIMS Patients receiving darunavir are advised to take it concomitantly with food. The objectives of the present cross-sectional study were to evaluate the actual concomitant food intake of patients visiting an HIV outpatient clinic. METHODS Sixty participants treated with darunavir/ritonavir once daily were subjected to a food recall questionnaire concerning their last concomitant food intake...

Several hematopoietic stem-cell (HSC) regulators are controlled by ubiquitinmediated proteolysis, so the ubiquitin pathway might modulate HSC function. However, this hypothesis has not been formally tested. Cul4A encodes a core subunit of one ubiquitin ligase. Whereas Cul4A-deficient embryos die in utero, Cul4A-haploinsufficient mice are viable but exhibit abnormal hematopoiesis (fewer erythroi...