نتایج جستجو برای: 246
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A tumour suppressor function for p53 is indicated in human lung cancer and in carcinoma of the colorectum. Loss of suppressor function, by mutation of the p53 gene, is associated with activation of p53 as an oncogene. The suppressor (wild type) and oncogenic (mutant) forms of the murine p53 protein are distinguishable at the molecular level by reactivity with anti-p53 monoclonal antibodies. For...
[This corrects the article on p. 246 in vol. 67.].
We have studied the correlated X-ray spectral and X-ray timing behavior of the Xray transient XTE J1806–246 using data obtained with the proportional counter array onboard the Rossi X-ray Timing Explorer. In the X-ray color-color diagram two distinct patterns are traced out. The first pattern is a curved branch, which is observed during the rise and the decay of the outburst. This pattern resem...
H EMOGLOBIN (Hb) K#{246}ln disease belongs to the group of nonspherocytic hemolytic anemias with a dominant inheritance pattern in which anemia is attributable to instability of the Hb molecule. The molecular pathology of this most common of the unstable Hbs was found to be the result of replacement of valine with methionine at f. 98 (FG 5), causing increased oxygen affinity and instability, po...
Many studies have shown that the mycoplasmal membrane protein p37 enhances cancer cell migration, invasion, and metastasis. Previously, we generated 6 monoclonal antibodies (MAbs) against the mycoplasmal protein p37 and showed the presence of mycoplasma-infected circulating tumor cells in the blood of hepatocellular carcinoma patients by using CA27, one of the six MAbs. When mycoplasmas were in...
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