Tumors H-59 and M-27, two stable metastatic variants of the Lewis lung carcinoma, differ in their ability to disseminate lymphatically. Tumor H-59 metastasizes to the regional lymph nodes regardless of the local site of growth and gives rise to widespread lymphatic dissemination, whereas tumor M-27 disseminates hematogenously without involvement of the regional nodes (P. Brodt, Cancer Res., 46:...

BACKGROUND In pregnancy, violence can have serious health consequences that could affect both mother and child. In Ghana there are limited data on this subject. We sought to assess the relationship between physical violence during pregnancy and pregnancy outcomes (early pregnancy loss, perinatal mortality and neonatal mortality) in Ghana. METHOD The 2008 Ghana Demographic and Health Survey da...

The effect of light on Monascus and the underlying mechanism have received a great deal of interest for the industrial application of Monascus pigments. In this study, we have examined the effects of blue light on the culture morphology, mycelium growth, pigments, and citrinin yield of Monascus in liquid-state and oscillation fermentation, and explored the mechanism at a physiological level. It...

An aryl trifluoromethyl diazirine photoreactive derivative was attached to the 2-thiocytidine residue at position 32 of tRNA(IArg) and this derivatized tRNA was bound to Escherichia coli 70S ribosomes. After irradiation at 350 nm the site of cross-linking to the 16S RNA was analyzed by our standard procedures and found to lie within the secondary structural element comprising bases 956-983; thi...

Artificially enforced expression of CD80 (B7-1) and CD86 (B7-2) on tumor cells renders them more immunogenic by triggering the CD28 receptor on T cells. The enigma is that such B7s interact with much higher affinity with CTLA-4 (CD152), an inhibitory receptor expressed by activated T cells. We show that unmutated CD80 is spontaneously expressed at low levels by mouse colon carcinoma cell lines ...

OBJECTIVE To examine differences in non-Hodgkin lymphoma (NHL) survival between young adults and children/adolescents. DESIGN Survival analysis using 13 Surveillance, Epidemiology, and End Results registries. SETTING Cancer survival information from population-based cancer registries from 1992 through 2001. PARTICIPANTS A total of 2442 cases of NHL among children/adolescents (aged 0-19 ye...

The two-source model for jet noise holds that turbulent mixing noise in jets is generated by uncorrelated, fine-scale (FSS) and partially correlated, large-scale (LSS) turbulent structures [Tam et al., J. Fluid Mech. 615, 253-292, (2008)]. The noise from an F-22A Raptor is modeled with an equivalent source consisting of two line arrays of monopole sources. These arrays, one correlated and one u...

Members of the Src family of kinases are abundant in platelets. Although their localization is known, their role(s) in platelet function are not well understood. Lyn is a Src-family kinase that participates in signal transduction pathways elicited by collagen-related peptide; it has also been implicated through biochemical studies in the regulation of von Willebrand factor signaling. Here, we p...

Severe paranoia is likely to limit engagement in physical activities. In this study we set out examine for the first time activity profiles of patients with current persecutory delusions and associations psychiatric symptoms. Seventy-five context non-affective psychosis wore a pedometer seven days. Participants completed measures meaningful activity, mobility, Latent class analysis was used ide...