219

219

Number 219

Intricate homeostatic mechanisms have been implicated in maintaining the blood glucose concentration over a narrow physiological range. The brain, as well as the peripheral organs such as pancreas, liver, and gastrointestinal tract, is able to sense the nutritional state and secretes specific hormones to maintain metabolic homeostasis. All of these cells contain a high-Km glucose-phosphorylatin...

Prion diseases are a group of etiologically heterogenous diseases. In addition to familial cases linked to mutations of PRNP open reading frame they include also cases of unknown etiology. One of the susceptibility factors to sporadic as well as iatrogenic prion diseases are PRNP polymorphisms. In the present study, we analyzed sequences of the PRNP gene codon 219 of 16 Polish CJD cases and we ...

Received: 1 December 2014, Revised: 28 February 2015, Accepted: 28 February 2015, Published: 30 June 2015 *Corresponding author: Shin-Young Yim, M.D., Ph.D. The Children’s Rehabilitation Clinic, Department of Physical Medicine and Rehabilitation, Department of Medical Genetics, Ajou University School of Medicine, 164 Worldcup-ro, Yeongtong-gu, Suwon 443-380, Korea. Tel: +82-31-219-5284, Fax: +8...