OBJECTIVES Administration of ethylene glycol monoalkyl ethers to rodents causes acute hemolytic anemia. Metabolic activation of these chemicals to alkoxyacetic acids is required to develop hemolytic effect. Current study was undertaken to compare the hemolytic activity of isopropoxyethanol (IPE) and phenoxyethanol (PhE) in male rats. The main goal of this study was to evaluate the role of alkyl...

One-third of protein formulations are multi-dose. These require antimicrobial preservatives (APs); however, some APs have been shown to cause protein aggregation. Our previous work on a model protein cytochrome c indicated that partial protein unfolding, rather than complete unfolding, triggers aggregation. Here, we examined the relative strength of five commonly used APs on such unfolding and ...

Mastitis is a mammary infection caused by the passage of pathogens into the mammary gland. Deteriorations in teat health are shown to be related to this type of infection [1]. Rough or cracked teats allow mastitis pathogens to colonize the udder. Roughness and cracking of the teat is related to hyperkeratosis, the condition of teat end callosity. Rough or cracked teats allow mastitis pathogens ...

New mono acid esters have been synthesized from the reaction of benzoic acid and mono-hydroxybenzoic acids with 2-phenoxyethanol separated from Urtica pilulifera, characterized, and screened for possible antioxidant, antifungal, antimicrobial and anticancer activities. These phenolic acid esters gave various degrees of free radical scavenging, but the values were lower than that of α-tocopherol...

In this study, we identify 11 mouse pup volatiles putatively involved in maternal care induction adult females. For purpose, have adapted the dynamic headspace methodology to extract volatolome of whole alive animals. Untargeted metabolomic was used compare neonatal (4–6 days) with elder pups until age weaning (21–23 days old). Pup analyzed by gas chromatography (GC) coupled single quadrupole m...

The production of H2 via electrolysis seems to be the best alternative traditional catalytic reforming processes. lignin allows produce pure while valorizing a low-price biomass waste with (theoretically) lower energy requirements than water electrolysis. Previous studies were published in last years dealing electro-oxidation on Ni-based catalysts. Ni is robust non-expensive metal that presents...

Mastitis is a mammary infection caused by the passage of pathogens into the mammary gland. Deteriorations in teat health are shown to be related to this type of infection [1]. Rough or cracked teats allow mastitis pathogens to colonize the udder. Roughness and cracking of the teat is related to hyperkeratosis, the condition of teat end callosity. Rough or cracked teats allow mastitis pathogens ...