A modified rapid slide agglutination test for the presumptive identification of Brucella canis infection in dogs has been developed. The method required mixing 0.1 ml of canine serum with 0.1 ml of 0.2 M 2-mercaptoethanol solution. Equal volumes (0.05 ml) of the treated serum and the B. canis plate antigen were mixed. Agglutination results were read within 2 min. Clinical studies showed 100% ag...

Development of a novel formulation of anticancer drugs to improve their water-solubility and bioavailability remains a great challenge. Herein, the potential anticancer agent 2-methoxyestradiol (2-ME) was selected as a model drug and was encapsulated within polyelectrolyte (PE) multilayers by layer-by-layer deposition of oppositely charged PEs onto the drug microcrystal surfaces. Cell viability...

CLINICAL CHEMISTRY, Vol. 23, No. 2, 1977 305 captoethanol was used per liter. We consider that this is due to the known tendency of mercaptoethanol to form aggregates with immunoglobulins, mainly IgG3 and 1gM (3-5). This observation was confirmed when we investigated the effect of two concentrations of mercaptoethanol (2.5 X i0 and 4.0 X 10 mol/liter) on the serum proteins, including immunoglob...