Chitin, a polysaccharide composed of β-(1–4)-linked 2-deoxy-2-acetamido-d-glucose units, is found in cell walls different organisms, including crustaceans, fungi, insects, some algae, microorganisms, and invertebrate animals, its deacetylation into chitosan confers it with incredible chemical versatility allowing to be processed numerous products [...]

Streptococcus lactis K1 has the capacity to grow on many sugars, including sucrose and lactose, in the presence of high levels (greater than 500 mM) of 2-deoxy-D-glucose. Initially, growth of the organism was transiently halted by the addition of comparatively low concentrations (less than 0.5 mM) of the glucose analog to the culture. Inhibition was coincident with (i) rapid accumulation of 2-d...

The yields of 2-deoxy-D-gluconic, D-gluconic and other sugar acids from 6 0 Co-gamma irradiated (dose rate = 4 Krads/min) D-glucose solutions are reported. The acids produced upon radiolyses were separated from glucose and neutral products by anion exchange, assayed by gas chromatography of the trimethylsilyl derivatives, and definitive identification made by mass spectrometry. In He degassed, ...

Regulation of hexitol catabolism was investigated in Streptococcus mutans, a cariogenic human dental plaque bacterium. Induction of hexitol catabolic enzymes and phosphoenolpyruvate:hexitol phosphotransferase and hexitol phosphate dehydrogenase activities was regulated by an inducer exclusion mechanism initiated by D-glucose and 2-deoxy-D-glucose. Kinetic analysis of the inhibitory effect of 2-...

Leclercq-Meyer, Viviane, Marcel M. Kadiata, and Willy J. Malaisse. Stimulation by 2-deoxy-D-glucose tetraacetates of hormonal secretion from the perfused rat pancreas. Am. J. Physiol. 276 (Endocrinol. Metab. 39): E689– E696, 1999.—The effects of aand b-2-deoxy-D-glucose tetraacetate (1.7 and 8.5 mM) on insulin, somatostatin, and glucagon secretion from isolated rat pancreases perfused in the pr...