نتایج جستجو برای: 1918

تعداد نتایج: 7085  

2016
E. S. Phipson

war, the engrossing problems which have followed in its wake, and the epidemic prevalence of influenza on a considerable scale within British shores have so fully occupied our attention that the calamitous happenings in India during 1918 may well have been somewhat obscured. Our minds, inured as it were, to the gigantic events of the past ten years, may have failed to appreciate fully the magni...

Journal: :Epidemiology and infection 2013
G D Shanks J F Brundage

Very few Pacific islands escaped the 1918-1919 influenza pandemic. Subsequent influenza epidemics in the established colonial outposts of American Samoa and New Caledonia infected many but killed very few persons whereas the extraordinarily isolated Niue, Rotuma, Jaliut and Yule islands experienced high mortality influenza epidemics (>3% of population) following 1918. These dichotomous outcomes...

Journal: :Cell 2005
Charles J. Russell Robert G. Webster

Pandemic influenza viruses pose a significant threat to public health worldwide. In a recent Nature paper, Taubenberger et al. (2005) now report remarkable similarities between the polymerase genes of the influenza virus that caused the 1918 Spanish influenza pandemic and those of avian influenza viruses. Meanwhile, Tumpey et al. (2005) reporting in Science show that the reconstructed 1918 Span...

2003
Guy Perrière Jean-François Dufayard Simon Penel Julien Grassot Laurent Duret Manolo Gouy

(1) Laboratoire de Biométrie et Biologie Évolutive, UMR CNRS 5558, Université Claude Bernard – Lyon 1, 43 bd. du 11 Novembre 1918, 69622 VILLEURBANNE Cedex – France {perriere,penel,duret,mgouy}@biomserv.univ-lyon1.fr (2) Unité de Recherche INRIA Rhône-Alpes, 655 av. de l’Europe, MONTBONNOT 38334 SAINT ISMIER Cedex – France [email protected] (3) Centre de Génétique Moléculaire ...

1944
Robert Heilig S. K. Visveswar

Since Wenkebach (1918) discovered that quinine is capable of abolishing extra systoles as well as auricular fibrillation, the attention of cardiologists has been centred mainly upon the action of this drug on disturbances of heart rhythm; this attitude was still more pronounced because of the wide use of the quinine isomer quinidine, introduced by Frey (1918) into the therapy of auricular and v...

2008

The isolated North Atlantic island of Bermuda, lying 1000 km ESE of Cape Hatteras, North Carolina, USA, has received scant attention from bryologists since the last compilations of nearly a century ago (EG Britton, 1918; Evans, 1918), plus a few additions (Andrews, 1923; Dixon, 1936). Of the mosses listed by EG Britton (1918), those that are not widespread in both Europe and North America are o...

Journal: :Cell host & microbe 2016
Jennifer Tisoncik-Go David J Gasper Jennifer E Kyle Amie J Eisfeld Christian Selinger Masato Hatta Juliet Morrison Marcus J Korth Erika M Zink Young-Mo Kim Athena A Schepmoes Carrie D Nicora Samuel O Purvine Karl K Weitz Xinxia Peng Richard R Green Susan C Tilton Bobbie-Jo Webb-Robertson Katrina M Waters Thomas O Metz Richard D Smith Yoshihiro Kawaoka M Suresh Laurence Josset Michael G Katze

Pandemic influenza viruses modulate proinflammatory responses that can lead to immunopathogenesis. We present an extensive and systematic profiling of lipids, metabolites, and proteins in respiratory compartments of ferrets infected with either 1918 or 2009 human pandemic H1N1 influenza viruses. Integrative analysis of high-throughput omics data with virologic and histopathologic data uncovered...

Journal: :The Journal of infectious diseases 2006
Adolfo Garcia-Sastre Richard J Whitley

The "Spanish influenza" pandemic of 1918 was the most devastating influenza epidemic reported in history and killed >30 million people worldwide. The factors contributing to the severe pathogenicity of this influenza virus are of great interest, because avian influenza viruses circulating today pose the threat of a new pandemic if they develop sustained human-to-human transmissibility. Recent c...

Journal: :Archives of biochemistry and biophysics 2017
Yves-Henri Sanejouand

The influenza pandemic of 1918-1919 killed at least 50 million people. The reasons why this pandemic was so deadly remain largely unknown [9]. However, It has been shown that the 1918 viral hemagglutinin allows to reproduce the hallmarks of the illness observed during the original pandemic [11]. Thanks to the wealth of hemagglutinin sequences accumulated over the last decades, amino-acid substi...

2008
Curtis R. Congreve Bruce S. Lieberman

Cladistic parsimony analysis of the trilobite family Homalonotidae Chapman 1980 produced a hypothesis of relatedness for the group. The family consists of three monophyletic subfamilies, one containing Trimerus Green 1832, Platycoryphe Foerste 1919, and Brongniartella Reed 1918; one containing Plaesiacomia Hawle and Corda 1847 and Colpocoryphe Novák in Perer 1918; and one containing Eohomalonot...

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