Exposure to 3TC of HIV-1 mutant strains containing non-nucleoside reverse transcriptase inhibitor (NNRTI)-specific mutations in their reverse transcriptase (RT) easily selected for double-mutant viruses that had acquired the characteristic 184-Ile mutation in their RT in addition to the NNRTI-specific mutations. Conversely, exposure of 3TC-resistant 184-Val mutant HIV-1 strains to nine differen...

microRNAs (miRNAs) are evolutionarily conserved, endogenous, small, noncoding RNA molecules of approximately 22 nucleotides in length that function as post-transcriptional gene regulators. Their aberrant expression may be involved in human diseases, including cancer. Although miRNA-184 (miR-184) has been reported in other tumors, its function in renal cell carcinoma (RCC) is still unknown. The ...

The purpose of this study was to investigate the relationship between the chemical form and localization of zinc (Zn) in plant leaves and their Zn accumulation capacity. An interspecific cross between Arabidopsis halleri sp. halleri and Arabidopsis lyrata sp. petrea segregating for Zn accumulation was used. Zinc (Zn) speciation and Zn distribution in the leaves of the parent plants and of selec...

Ovarian clear cell carcinoma (OCCC) is a rare subtype of epithelial ovarian with poor prognosis in advanced stages and recurrent disease. Recent literature on outcomes clinical practice for OCCC including stage (stage III IV) limited. A retrospective review patients treated at The Royal Marsden between March 2003 July 2022 was conducted. Demographic clinicopathologic factors were abstracted eva...

Introduction .............................................................................................................. 179 Signaling Methods ................................................................................................................................. 180 Signal Complexity and Patterns .........................................................................................

Factory, 184abstract representation, 21activation states, 64Adapter, 194AHM, 61, 63–68, 131–149, 203–206, 231AnchorId, 113AnchorValue, 113animation, 104API, 31architectural form, 84, 85atemporal composition, 63Atomic, 117 BaseInstantiation, 124Berlageenvironment, 7, 165, 177, 202–215, 221,222meta-DTD, 208Berners-Lee, 5, 73, 74, 91<...

In the present study, rare earth elements (REEs, i.e., La, Ce, Nd, and Pr) were hydrometallurgically recovered in oxalate form with presence of very low concentration Co, Al, Zn Ni from solution after processing spent Nickel metal hydride (Ni-MH) batteries. The mixture was used as alternative source synthesis magnetocaloric materials. this a manganite sample general formula ABO 3 selected to be...

A new concept in multifunctional anticancer agents is demonstrated. Tetrakis-(diisopropyl-guanidino) zinc phthalocyanine (Zn-DIGP) exhibits excellent properties as a photodynamic therapy (PDT) agent, as well as potential anti-metastatic activities in vivo. Zn-DIGP exhibits good cellular uptake and low toxicity in the dark (EC50 > 80 μM) and is well tolerated upon its intravenous injection into ...