Repeated measures can occur on subjects that are nested within clusters. The clusters may be considered a random effect. Then the covariance structure must accommodate between-cluster variance as well as within-cluster covariance. There also may be higher levels of clustering. In addition, there may be other fixed effect factors that are crossed with some or all of the random effects. The covar...

We present two epoch polarimetric images of the BL Lac object 0735+178 obtained with the Very Long Baseline Array at 22 and 43 GHz. These images provide the highest resolution observations of this source to date, and show a twisted jet with two sharp apparent bends of 90 within two milliarcseconds of the core. The magnetic field appears to smoothly follow one of the bends in the jet, suggesting...

We report the results of deep Hα imaging of the ionized gas surrounding the low-redshift (z = 0.0638) quasar MR 2251–178 using the TAURUS Tunable Filter (TTF) on the Anglo-Australian Telescope. Our observations reach a 2-σ detection level of ∼ 5 × 10 −18 erg s −1 cm −2 arcsec −2 , more than an order of magnitude deeper than conventional narrowband images previously published on this object. Our...

The CCAAT box is one of the most common elements in eukaryotic promoters, found in the forward or reverse orientation. Among the various DNA binding proteins that interact with this sequence, only NF-Y (CBF, HAP2/3/4/5) has been shown to absolutely require all 5 nt. Analysis of a database with 178 bona fide NF-Y binding sites in 96 unrelated promoters confirms this need and points to specific a...

We have studied the genetic diversity of the TCR repertoire to the murine alloantigen I-Abm12 by generating a panel of 178 C57BL/10-derived I-Abm12-reactive T cell hybridomas. The expression of V alpha and V beta gene families was examined in this panel and the frequency of expression of V beta, but not ofV alpha, gene families differed significantly from that observed in a companion panel of r...

The mass balance and metabolite profiles of 2-(2-amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)[U-(14)C]phenyl]acetamide ([(14)C]mirabegron, YM178), a β(3)-adrenoceptor agonist for the treatment of overactive bladder, were characterized in four young, healthy, fasted male subjects after a single oral dose of [(14)C]mirabegron (160 mg, 1.85 MBq) in a solution. [(14)C...

AIM OF THE STUDY Thyroid carcinoma is the most common malignancy of endocrine organs. The prognosis varies. Factors such as age, sex, size of the tumor, stage of disease, presence of extrathyroidal spread, and completeness of resection have been found to significantly influence prognosis. We aimed to evaluate clinical features of our patients with thyroid carcinoma, prospectively. MATERIAL AN...

Emission from Active Galactic Nuclei is known to vary strongly over time over a wide energy band, but the origin of the variability and especially of the inter-band correlations is still not well established. Here we present the results of our X-ray and optical monitoring campaign of the quasar MR 2251-178, covering a period of 2.5 years. The X-ray 2–10 keV flux is remarkably well correlated wi...

Our study aims to investigate and describe the epidemiology of the intestinal carriage of ESBLPS in intensive care units of five Lebanese hospitals and to analyze the potential risk factors for the acquisition of these strains. At the same time, we intend to determine the patterns of susceptibility of these strains, exploring therefore the availability of alternative treatment. One thousand, fo...