نتایج جستجو برای: 1754

تعداد نتایج: 472  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1992
P E Leon H Raventos E Lynch J Morrow M C King

Primary--i.e., nonsyndromal-postlingual deafness is inherited as an autosomal dominant phenotype in a large kindred in Costa Rica. Genetically susceptible individuals begin to lose hearing at low frequencies at about age 10 years, after language and speaking are learned. Deafness inevitably progresses by age 30 years to bilateral hearing loss of all frequencies. Intelligence, fertility, and lif...

Journal: :Revista de história da sociedade e da cultura 2022

Os decretos emanados do Concílio de Trento (1545-1563) estabeleciam a primazia pontífice no escrutínio e julgamento dos bispos em “causas criminais”, contudo, na prática, as inquirições seguiram caminhos diversos. Este artigo examinará, portanto, os mecanismos jurídicos instrumentos utilizados pelos tribunais régios eclesiásticos para investigar julgar procedimentos da América portuguesa partir...

2014
Iñigo Olalde Federico Sánchez-Quinto Debayan Datta Urko M. Marigorta Charleston W. K. Chiang Juan Antonio Rodríguez Marcos Fernández-Callejo Irene González Magda Montfort Laura Matas-Lalueza Sergi Civit Donata Luiselli Philippe Charlier Davide Pettener Oscar Ramírez Arcadi Navarro Heinz Himmelbauer Tomàs Marquès-Bonet Carles Lalueza-Fox

A pyrographically decorated gourd, dated to the French Revolution period, has been alleged to contain a handkerchief dipped into the blood of the French king Louis XVI (1754-1793) after his beheading but recent analyses of living males from two Bourbon branches cast doubts on its authenticity. We sequenced the complete genome of the DNA contained in the gourd at low coverage (~2.5×) with coding...

Journal: :The Journal of pharmacology and experimental therapeutics 2011
Edwin K Jackson Delbert G Gillespie Raghvendra K Dubey

Studies show that kidneys produce 2',3'-cAMP, 2',3'-cAMP is exported and metabolized to 2'-AMP and 3'-AMP, 2'-AMP and 3'-AMP are metabolized to adenosine, 2',3'-cAMP inhibits proliferation of preglomerular vascular smooth muscle cells (PGVSMCs) and glomerular mesangial cells (GMCs), and A(2B) (not A(1), A(2A), or A(3)) adenosine receptors mediate part of the antiproliferative effects of 2',3'-c...

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