Fatty acid amide hydrolase (FAAH) and monoglyceride lipase (MGL) catalyse the hydrolysis of the endocannabinoids anandamide and 2-arachidonoyl glycerol. We investigated their ultrastructural distribution in brain areas where the localization and effects of cannabinoid receptor activation are known. In the hippocampus, FAAH was present in somata and dendrites of principal cells, but not in inter...

In vivo targeting of C-type lectin receptors is an effective strategy for increasing antigen uptake and presentation by dendritic cells (DCs). To induce efficient immune response, glycosylated tumor-associated Tn antigens were used to target DCs through binding to macrophage galactose-type lectin (MGL). The capacity of Tn-glycosylated antigens-and the multiple antigenic glycopeptide Tn3 therape...

OBJECTIVE The aim of this study was to evaluate how different parameters of short-term glycemic control would correlate with the perception of health-related quality of life (HRQoL) in patients with type 1 diabetes mellitus (T1D). SUBJECTS AND METHODS A total of 50 T1D patients aged 18 to 50 years were evaluated with the questionnaires Problem Areas in Diabetes (PAID) scale and Diabetes Quali...

An investigation was carried out to decipher the effect of genotypes and concentrations growth regulators for callus induction subsequent plant regeneration from mature seeds rice. Two local rice cultivars viz. Nayanmony Kalomona two 2, 4-D NAA were used evaluate their performance. The cultured under aseptic condition onto MS basal medium at varying combinations (1.0, 1.5 2.0 mgL- 1) (0.0, 0.5 ...

mGluRs (metabotropic glutamate receptors) are G-protein-coupled receptors that play an important neuromodulatory role in the brain. Glutamatergic transmission itself plays a fundamental role in the simple nervous system of the model organism Caenorhabditis elegans, but little is known about the contribution made by mGluR signalling. The sequenced genome of C. elegans predicts three distinct gen...

The physicochemical characterization of the textile industry effluent collected from Oswal Textile Industries, Ludhiana (Punjab.) India has been carried out and the results showed that the temperature (40°C), pH (8.00), Biological Oxygen Demand (260 mgl –1 ), Chemical Oxygen Demand (790 mgl –1 ), Total Suspended Solids (2000 mgl –1 ), Total Dissolved Solids (7000 mgl –1 and colour over the pres...

Our aim was to describe sperm parameters in residents from Northern Chile. We evaluated in 101 volunteers (18 and 30 years old) urinary and drinking water Boron levels using Inductively Coupled Plasma Mass Spectrometry; semen parameters were measured with standardized methods. Each individual was categorized in 3 levels of exposure: low (B levels in urine ≤ 2.94 mgL1 or tap water ≤ 3.0 mgL-1), ...

Background & Aim: Lemon verbena (Lippia citriodora H.B.K.) is a richly scented herb and has a long history as a sacred and medicinal plant. Select an appropriate medium in tissue culture is a necessity for success Experimental: To evaluate the effect of 10 medium of previous researches for Lippia micropropagation (1- MS medium supplemented with BAP (3 mgL-1) + IBA ...

In atopic dermatitis (AD) and psoriasis (Pso), inflammatory skin diseases with a high patient burden, understanding which subsets of dendritic cells (DCs) macrophages (MØs) are involved in the disease pathogenesis remains key to developing effective treatments. Limited subpopulations DCs MØs that thought drive Th2-mediated immune responses mice express macrophage galactose-type C-type lectin (M...