نتایج جستجو برای: 13c chemical shift
تعداد نتایج: 516315 فیلتر نتایج به سال:
In this article we present 1H and 13C chemical shift assignments, secondary structural propensity data and normalized temperature coefficient data for N-terminal peptides of Connexin 26 (Cx26), Cx26G12R and Cx32G12R mutants seen in syndromic deafness and Charcot Marie Tooth Disease respectively, published in "Structural Studies of N-Terminal Mutants of Connexin 26 and Connexin 32 Using 1H NMR S...
A recently determined set of 20 NMR-derived conformations of a 48-residue all-alpha-helical protein, (PDB ID code 2JVD), is validated here by comparing the observed (13)C(alpha) chemical shifts with those computed at the density functional level of theory. In addition, a recently introduced physics-based method, aimed at determining protein structures by using NOE-derived distance constraints t...
We present here continuous records of 8180 and t~13C in benthic foraminifera, extending well into the last ice age, in two piston cores from the Andaman Sea (sill depth ~ 1.3 km) and the Bay of Bengal (3 km). These show that, contrary to the previous reports, the glacial to interglacial shift in 613C at mid-depths in the Northeast Indian Ocean was indistinguishable from the mean oceanic 313C ch...
We have examined the 13C~ and 13C[3 chemical shifts of a number of proteins and found that their values at the N-terminal end of a helix provide a good predictor for the presence of a capping box. A capping box consists of a hydrogen-bonded cycle of four amino acids in which the side chain of the N-cap residue forms a hydrogen bond with the backbone amide of the N3 residue, whose side chain in ...
pH is a tightly regulated physiological parameter that is often altered in diseased states like cancer. The development of biosensors that can be used to non-invasively image pH with hyperpolarized (HP) magnetic resonance spectroscopic imaging has therefore recently gained tremendous interest. However, most of the known HP-sensors have only individually and not comprehensively been analyzed for...
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