we report 127 cases who have had elective operation on cranium because of skull bone defect during 1984-1989. usually repair of skull bone defect and preserving normal anatomy were the major therapeutic goals. 10, ii in these cases a new surgical technique is described which can successfully accomplish these goals in a single but staged operative procedure.

MicroRNAs play significant roles in development, metabolism and carcinogenesis, however, limited information is available about their primary transcripts and the transcriptional regulation of the microRNA genes. We report here the cloning of two primary miRNAs (pri-miR-433 and pri-miR-127) encoded by the miR-433-127 locus. Using both database mining and experimental methods, we isolated the ful...

Central nervous system (CNS) malformations represent important factor of morbidity and mortality in children. The aim of the study was to determine the incidence, type and clinical features of CNS malformations in children who were admitted at the Neonatal and Child Neurology Department, Neonatal Intensive Care Unit and Paediatric Intensive Care Unit of Paediatric Clinic, University of Sarajevo...

Cellular senescence occurs as a response to extracellular and intracellular stresses and contributes to aging and age-related pathologies. Emerging evidence suggests that cellular senescence also acts as a potent tumor suppression mechanism that prevents the oncogenic transformation of primary human cells. Recent reports have indicated that miRNAsact as key modulators of cellular senescence by ...

Concentrations and species of iodine isotopes ((127)I and (129)I) provide vital information about iodine geochemistry, environmental conditions and water masses exchange in oceans. Despite extensive investigations of anthropogenic (129)I in the Arctic Ocean and the Nordic Seas, concentrations of the isotope in the Atlantic Ocean are, however, still unknown. We here present first data on (129)I ...

Introducción: se han descrito cambios morfológicos asociados a la infección gástrica por H. como: gastritis crónica superficial, atrófica, folicular y metaplasia intestinal. Importancia: La atrofia pertenecen cascada de histológicos que conducen al cáncer gástrico.
 Metodología: estudio retrospectivo corte transversal en el analizaron pacientes con dispepsia; durante su examen practicó end...

BACKGROUND AND PURPOSE Various modifications of detachable coils have been attempted to reduce recurrence rates in aneurysmal coil embolization and HydroSoft coil is one of them. The authors report their experience using HydroSoft coils in the treatment of cerebral aneurysms. MATERIALS AND METHODS The present study is a prospective multicenter observational series of 127 aneurysms in 120 pati...