Abstract Purpose of Review This narrative review reflects on the body evidence cardiac 123 I- m IBG imaging that has accumulated since introduction in late 1970s and focusses to what extent fulfilled its potential cardiology especially. Recent Findings In contrast linear relationship between IBG-derived parameters overall prognosis heart failure, there seems a “bell-shape” curve for arrhythmic ...

Parkinson’s disease (PD) is a relatively common neurological disorder in the elderly. However, only 76% of patients considered clinically to have PD are confirmed to have PD after postmortem examination (Hughes et al., 1993). The most common atypical form of parkinsonism is multiple system atrophy (MSA) (Hughes et al., 1994). MSA is clinically characterized by a combination of parkinsonian, aut...

UNLABELLED Sympathetic overactivity has been noted in various clinical stages of essential hypertension. The purpose of this study is to investigate 123I-metaiodobenzylguanidine (MIBG) uptake and washout in patients with borderline and mild hypertension. METHODS To assess cardiac sympathetic function in essential hypertension, we performed 123I-MIBG cardiac imaging and echocardiography in 25 ...

Changes in the function of the adrenergic neurons of the heart may be important indicators of the adaptations of an animal to physiologic stress and disease. Rates of loss of norepinephrine (NE) from the heart were considered to be proportional to NE secretion and to adrenergic function. In rat hearts, yohimbine induced almost identical increases in rates of loss of 3H-NE and of 125I-metaiodobe...

radioiodinated meta iodobenzylguanidine (mibg) is one of the important radiopharmaceuticals in nuclear medicine. [123/131i]mibg is used for imaging of adrenal medulla, studying heart sympathetic nerves, treatment of pheochromacytoma and neuroblastoma. for clinical application, radioiodinated mibg is prepared through isotopic exchange method, which includes replacement of radioactive iodine in a...

in this study, l-131-mibg imaging was performed in 44 patients with clinical suspicion of tumors originating from neuro-endocrine system. the patients were referred to our department following plasma and urinary measurement of epinephrine, norepinehrine and vanilmandelic acidfvma). radionuclide imaging was performel as a comparative or confirmatory measure in all patients who had previous abdom...

Parkinson’s disease (PD) is one of the most common neurological disorder diseases which takes place when brain cells gradually die. PD considered a challengeable because similarities between and other disorders. For this reason, there are several ways to diagnose PD. Nuclear medicine can be solution distinguish some disorders The aim review understand differences three radiopharmaceuticals used...