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Promoter DNA hypermethylation is an important biomarker of hepatocellular carcinoma (HCC), supporting the potential utility of demethylating agents in this disease. Guadecitabine (SGI-110) is a second-generation hypomethylating agent formulated as a dinucleotide of decitabine and deoxyguanosine that yields longer half-life and more extended decitabine exposure than decitabine IV infusion. Here ...

background: weissellicin 110 is the only bacteriocin reported in weissella cibaria up to now. this bacteriocin represents several unique features. this is the first report on the gene sequence that encodes for the bacteriocin.objectives: providing a rapid detection method to isolate the weissellicin 110 encoding gene and determination of the bacteriocin distribution were the objectives.material...