Abstract Background Interleukin (IL)-10 is one of the key interleukins in immune system. It plays an anti-inflammatory role body by inhibition synthesis pro-inflammatory cytokines and reducing expression major histocompatibility complex II molecules. The single-nucleotide polymorphism gene this interleukin affects its level. Thus, study was conducted to investigate IL-10 at position -1082A/G Az...

Background: Deoxyribozymes (Dzs) can play a role as gene expression inhibitors at mRNA level. Among Dzs, the 10-23 deoxyribozyme has significant potentials for treatment of diseases. Designed Dz includes a catalytic core made of 15 deoxyribonucleotides and two binding arms consisted of 6-12 nucleotides for site specific binding to target RNA and hydrolysis. The enzyme has characteristic feature...

INTRODUCTION The Sextupole lens and its followed modifications described in [1]-[3]. Due to peculiarity of design it was possible to modify the poles of Sextupole with minor efforts. The coils remain the same as in original design. The sextupole coil has 160 turns/coil, which delivers 1.6 kA-turns for 10A feeding current. The Dipole corrector coil has 270 turns each and was run up to 20A pick c...