Pigment grade titanium dioxide is composed of sub-micron sized particles, including a nanofraction, and is widely utilized in food, cosmetic, pharmaceutical, and biomedical industries. Oral exposure to pigment grade titanium dioxide results in at least some material entering the circulation in humans, although subsequent interactions with blood immune cells are unknown. Pigment grade titanium d...

BACKGROUND Community-associated methicillin-resistant Staphylococcus aureus outbreaks have occurred in individuals engaged in athletic activities such as wrestling and football. Potential disease reduction interventions include the reduction or elimination of bacteria on common use items such as equipment. Chlorine dioxide has a long history of use as a disinfectant. The purpose of this investi...

The authors investigated the relation between ambient concentrations of five of the Environmental Protection Agency's criteria pollutants and asthma exacerbations (daily symptoms and use of rescue inhalers) among 990 children in eight North American cities during the 22-month prerandomization phase (November 1993-September 1995) of the Childhood Asthma Management Program. Short-term effects of ...

The aim of the present study was to determine whether donitriptan and sumatriptan decreased jugular venous oxygen saturation and increased carbon dioxide partial pressure in venous blood. However, previous studies conducted with these compounds cannot discriminate whether the decrease of venous oxygen saturation is dependent of cranial vasoconstrictor. In the present study, vehicle (n = 10), do...

INTRODUCTION The respiratory effects (changes in pH and PaCO(2)) of carbon dioxide insufflation in thoracoscopic surgery in adult patients with pulmonary disease were not documented previously. METHODS In this observational study 21 patients scheduled for elective thoracoscopic surgery with one lung ventilation using a double lumen tube and intraoperative carbon dioxide insufflation were stud...

During the past few years there has been a growing appreciation of the role of carbon dioxide in bacteriology. It has been demonstrated by a number of observers that the presence of carbon dioxide is apparently necessary for growth of all species of bacteria so far studied. Walker (1932) and Gladstone et al. (1935) suggest that the lag phase of the bacterial growth cycle is due to the failure o...

Decontamination of bacterial endospores such as Bacillus anthracis has traditionally required the use of harsh or caustic chemicals. The aim of this study was to evaluate the efficacy of a chlorine dioxide decontaminant in killing Bacillus anthracis spores in solution and on a human skin simulant (porcine cadaver skin), compared to that of commonly used sodium hypochlorite or soapy water decont...

Hyperventilation (HV) is commonly used to extend breath-hold time by eliminating carbon dioxide to delay the hypercapnic stimulus to end breath-hold. The chief hazard is that loss of consciousness may result from hypoxia before the hypercapnic drive initiates a breathing cycle. The purpose of this study is to evaluate the efficacy of oxygen inspiration to improve the safety of breath-holding te...

Representative strains of anaerobic bacteria from human infections were used to evaluate broth media, gas mixtures, and inocula for use in developing a procedure for performing minimal inhibitory concentration antimicrobic susceptibility tests. Nine commercially available media, including two that were chemically defined, were tested. Tests were performed in atmospheres with carbon dioxide conc...