Investigations on the transfer of the ligand, imidazole (HIm), between two covalently linked redox centres--zinc porphyrin and phenylenediamine (PD)--and the influence of the length of the linker are reported. Since the binding affinity of the ligand with zinc porphyrin is different from that of the ligand with the phenylenediamine moiety, the transfer of the ligand could be electrochemically c...

Synthesis of Some Benzimidazole derivatives 4'-(5, 6-substitued-2-trifluoromethylbenzoimidazol-1-ylmethyl)-biphenyl-2-carboxylic acid were synthesized by condensation of various steps with different o-Phenylenediamine was condensed with in propylene glycol was added trifluoroacetic acid in the presence of BF3•OEt2 as catalysis. Elemental analysis, IR, 1HNMR and mass spectral data confirmed the ...

The interactions of a series of platinum(II) Schiff base complexes with c-myc G-quadruplex DNA were studied. Complex [PtL(1a)] (1 a; H(2)L(1a)=N,N'-bis(salicylidene)-4,5-methoxy-1,2-phenylenediamine) can moderately inhibit c-myc gene promoter activity in a cell-free system through stabilizing the G-quadruplex structure and can inhibit c-myc oncogene expression in cultured cells. The interaction...

A novel type of leaf-like poly (p-phenylenediamine) (PpPD) microcrystal was prepared under mild conditions, which was successfully applied to the visual detection of Co(2+)in vitro and in tissue based on the extinction and light scattering features owing to the special etching effect of Co(2+) on the surface of the leaf-like microcrystal.

An efficient one-pot oxidation/condensation tandem process has been developed for the synthesis of 2-substituted benzimidazole derivatives from benzylic alcohols and 1,2-phenylenediamine with use of urea-hydrogen peroxide/silica phosphoric acid  as a bifunctional catalyst. This method provides a rapid and efficient access to 2-substituted benzimidazoles.

The Cosmetic Ingredient Review Expert Panel (CIR Panel) reviewed the safety of hydroxypropyl bis(N-Hydroxyethyl-p-Phenylenediamine) HCl, which functions as an oxidative hair dye ingredient. The Panel considered relevant animal and human data provided in this safety assessment and concluded that hydroxypropyl bis(N-hydroxyethyl-p-phenylenediamine) HCl is safe for use in oxidative hair dye formul...

The aim of this present study was to synthesize 2-substituted and 1,2-disubstituted benzimidazole derivatives to investigate their antibacterial diversity for possible future drug design. The structure-based design of precursors 2-(1H-benzimidazol-2-yl)aniline 1, 2-(3,5-dinitro phenyl)-1H-benzimidazole 3 and 2-benzyl-1H-benzimidazole 5 were achieved by the condensation reaction of o-phenylenedi...