نتایج جستجو برای: 023
تعداد نتایج: 1573 فیلتر نتایج به سال:
Neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) primarily manifests in neonates or infants with hepatomegaly, liver dysfunction, and hypoglycemia. This study investigated the functions of islet beta cells and their correlations with liver dysfunction in NICCD patients.We retrospectively analyzed clinical data on liver function and islet beta cell functions for 36 patients ...
Toll-like receptors (TLRs) play a key role in sensing microbial components and hence in eliciting innate immune responses. Lipopolysaccharide (LPS)-induced dimerization of TLR4 is a prerequisite for the activation of downstream signaling cascade including nuclear factor-kappa B (NF-κB). Hence, the receptor dimerization is a primary regulatory event in the activation of TLRsignaling which could ...
OBJECTIVES African Americans as a group have higher blood pressure than individuals of northern European ancestry (non-Hispanic Whites). We investigate whether psychosocial factors explain the resting blood pressure of healthy, community-dwelling African Americans in our study. PARTICIPANTS A convenience sample of self-reported normotensive African Americans aged 18-65 years who live in the N...
Influence of age on the CD4 cell response to highly active antiretroviral therapy (HAART) was examined in 1956 patients (median age, 37.2 years) in the EuroSIDA study. Median initial CD4 cell count was 192x106 cells/L, follow-up was 31 months, and time to maximum CD4 cell response was 20 months. Age groups were not different for baseline CD4 cell count, baseline human immunodeficiency virus RNA...
Any goal within the flight range of the bee is characterized by direction and distance from the hive. These two parameters are also the basic in formations transmitted in bee dances. The direc tion has to be calculated by using an individually acquired sun compass, whereas the distance is esti mated by the amount of energy invested during the flight [1], Local and distant landmarks are used ...
Typical assays used to discover and analyze small molecules that inhibit the hepatitis C virus (HCV) NS3 helicase yield few hits and are often confounded by compound interference. Oligonucleotide binding assays are examined here as an alternative. After comparing fluorescence polarization (FP), homogeneous time-resolved fluorescence (HTRF®; Cisbio) and AlphaScreen® (Perkin Elmer) assays, an FP-...
PURPOSE To evaluate the effect of Amplatz sheath size used in percutaneous nephrolithotomy (PCNL) on postoperative outcomes, bleeding and renal impairment rates. MATERIALS AND METHODS We retrospectively evaluated the records of 91 patients who had undergone PCNL. We divided the patients into 2 groups according to Amplatz sheath size (22 and 30 French [F]) used in the PCNL procedure. Groups we...
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