Secretion of cell wall-bound acid phosphatase by Saccharomyces cerevisiae occurs along a restricted portion of the cell surface. Acid phosphatase activity produced during derepressed synthesis on a phosphate-limited growth medium is detected with an enzymespecific stain and is localized initially to the bud portion of a dividing cell . After two to three generations of phosphate-limited growth,...

HIV/AIDS as well as substance use disorders continue to devastate the African American community. Black women have the highest rate of new HIV infections among all groups of American women, with more than twice the prevalence rate of white or Hispanic women. Substance use and its correlation to HIV is well documented, particularly within America's urban setting. As a result, multiple approaches...

We have examined the carbohydrate specificity of bindin, a sperm protein responsible for the adhesion of sea urchin sperm to eggs, by investigating the interaction of a number of polysaccharides and glycoconjugates with isolated bindin. Several of these polysaccharides inhibit the agglutination of eggs by bindin particles. An egg surface polysaccharide was found to be the most potent inhibitor ...

Bone metastasis affects more than 70% of advanced breast cancer patients, but the molecular mechanisms of this process remain unclear. Here, we present clinical and experimental evidence to clarify the role of the integrin b-like 1 (ITGBL1) as a key contributor to bone metastasis of breast cancer. In an in vivo model system and in vitro experiments, ITGBL1 expression promoted formation of osteo...

In this article a group-theoretical aspect of the method of dimensional reduction is presented. Then, on the base of symmetry analysis of an anisotropic space geometrical description of dimensional reduction of equations for vector massless field is given. Formula for calculating components of the energymomentum tensor from the variables of the field factor-equations is derived. The covariant e...

1 I n t r o d u c t i o n This paper applies the idea of conspiracy numbers [McAllester, 1988] to derive two heuristic algorithms for searching and/or trees. The first algorithm turns out to be a member of the class of A O * best-first algo­ r i thms [Nilsson, 1980], but it conforms to the principle of sunk costs (a rule of economic rationality not respected by tradit ional and/or tree search a...

Population incidence of Guillain-Barré syndrome (GBS) is required to assess changes in GBS epidemiology, but published estimates of GBS incidence vary greatly depending on case ascertainment, definitions, and sample size. We performed a meta-analysis of articles on GBS incidence by searching Medline (1966–2009), Embase (1988–2009), Cinahl (1981–2009) and CABI (1973–2009) as well as article bibl...

We describe a method for the calculation of guaranteed bounds for the K lowest eigenvalues of second-order problems with Neumann boundary conditions. Using P2 approximations for the eigenfunctions and RT1 approximations for the gradients of the eigenfunctions in H(div; ), an error bound for the eigenfunctions is established for weak approximations in H1( ). In addition, the rest of the spectrum...

Population incidence of Guillain-Barré syndrome (GBS) is required to assess changes in GBS epidemiology, but published estimates of GBS incidence vary greatly depending on case ascertainment, definitions, and sample size. We performed a meta-analysis of articles on GBS incidence by searching Medline (1966–2009), Embase (1988–2009), Cinahl (1981–2009) and CABI (1973–2009) as well as article bibl...