Abstract Introduction Approximately 10,000 patients undergo cystectomy with ileal conduit diversion annually in the USA, of which ∼ 50% will subsequently develop a parastomal hernia (PSH) at 2 years. Due to knowledge gap between urostomy surgical factors and abdominal wall forces, we developed silicone ex-vivo human cadaver fascia-based model for study. Our objective was measure relationship in...

Serine palmitoyltransferase (SPT) plays the key role on catalysing formation of 3-ketodihydrosphingosine, which is first step de novo biosynthesis sphingolipids. SPT linked to many diseases including fungal infection, making it a potential therapeutic target. Thus, logical docking-based virtual screening method was used screen selective inhibitor against fungi, not human. We myriocin-similarity...

Introduction Data on the epidemiology of familial Mediterranean fever (FMF) and the prevalence of disease causing mutations among different ethnic groups and geographical regions around the world are insufficient. The prevalence of mutations that account for FMF in Turkey has been defined in the past by determining the frequency of MEFV mutations in affected individuals or in hospital-based con...

PURPOSE This study aimed to evaluate stress distribution on peri-implant bone simulating the influence of platform switching in external and internal hexagon implants using three-dimensional finite element analysis. MATERIALS AND METHODS Four mathematical models of a central incisor supported by an implant were created: External Regular model (ER) with 5.0 mm × 11.5 mm external hexagon implan...

Introduction: Both breast cancer and radiation therapy (RT) have been associated with an increased risk of bullous pemphigoid (BP). In the setting RT, majority patients develop BP following completion treatment, a mean time to onset 15.8 months1. Case Report: A 68-year-old Black female history ductal carcinoma right status post partial mastectomy sentinel lymph node biopsy RT was referred Oncod...