AIM
To determine the effect of combined serelaxin and rosiglitazone treatment on established hepatic fibrosis.
METHODS
Hepatic fibrosis was induced in mice by carbon tetrachloride administration for 6 wk, or vehicle alone (nonfibrotic mice). For the final 2 wk, mice were treated with rosiglitazone, serelaxin, or both rosiglitazone and serelaxin. Serum liver enzymes and relaxin levels were det...
