نتایج جستجو برای: ژن cuznsod

تعداد نتایج: 16016  

Journal: :Inorganic chemistry 2005
Vladimir Pelmenschikov Per E M Siegbahn

The mechanism for the toxic superoxide radical disproportionation to molecular oxygen and hydrogen peroxide by copper-zinc superoxide dismutase (CuZnSOD) has been studied using the B3LYP hybrid density functional. On the basis of the X-ray structure of the enzyme, the molecular system investigated includes the first-shell protein ligands of the two metal centers as well as the second-shell liga...

Journal: :Physiological research 2001
N Petrović G Cvijić V Davidović

The activity of antioxidant enzymes, copper-zinc superoxide dismutase (CuZnSOD), manganese superoxide dismutase (MnSOD) and catalase (CAT), as well as that of the mitochondrial FAD-dependent alpha-glycerophosphate dehydrogenase (alpha-GPD) in the rat interscapular brown adipose tissue (IBAT) were studied after the treatment with methimazole (MMI) for three weeks or with iopanoic acid (IOP) for ...

2013
Lucie Vávrová Jana Kodydková Miroslav Zeman Magdaléna Dušejovská Jaroslav Macášek Barbora Staňková Eva Tvrzická Aleš Žák

OBJECTIVE In the pathogenesis of the metabolic syndrome (MetS), an increase of oxidative stress could play an important role which is closely linked with insulin resistance, endothelial dysfunction, and chronic inflammation. The aim of our study was to assess several parameters of the antioxidant status in MetS. METHODS 40 subjects with MetS and 40 age- and sex-matched volunteers without MetS...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2012
Pamela Christudoss R Selvakumar Anna B Pulimood Jude Joseph Fleming George Mathew

Trace element zinc deficiency or excess is implicated in the development or progression of some cancers. The exact role of zinc in the etiology of colon cancer is unclear. To cast light on this question, an experimental model of colon carcinogenesis was applied here. Six week old rats were given sub cutaneous injections of DMH (30 mg/kg body weight) twice a week for three months and sacrificed ...

Journal: :The European respiratory journal 2004
T Harju R Kaarteenaho-Wiik R Sirviö P Pääkkö J D Crapo T D Oury Y Soini V L Kinnula

Oxidant stress is a key mechanism for smoking-induced chronic obstructive pulmonary disease (COPD). Smoking has been shown to upregulate several antioxidant enzymes, with potential effects on the prevention of the disease and/or its progression. Superoxide dismutases (SOD)s are the only enzymes capable of consuming superoxide radicals. The purpose of the present study was to investigate SODs in...

Journal: :Journal of plant physiology 2012
Yun-Hee Kim Jae Cheol Jeong Seyeon Park Haeng-Soon Lee Sang-Soo Kwak

Two ethylene response factor (ERF) genes, IbERF1 and IbERF2, were isolated from a library of expressed sequence tags (EST) prepared from suspension-cultured cells and dehydration-treated fibrous roots of sweetpotato (Ipomoea batatas). The deduced IbERFs contained a nuclear localization signal and the AP2/ERF DNA-binding domain. RT-PCR analysis revealed that IbERF1 was expressed abundantly durin...

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