The assembly of bacteriophage PRD1 proceeds via formation of empty procapsids containing an internal lipid membrane, into which the linear double-stranded DNA genome is subsequently packaged. The packaging ATPase P9 and other putative packaging proteins have been shown to be located at a unique vertex of the PRD1 capsid. Here, we describe the isolation and characterization of a suppressor-sensi...

Nontypeable Haemophilus influenzae (NTHI) is a major pathogen of otitis media. One of the outer membrane proteins of NTHI, P6, is an antigen common to all strains and is considered as a candidate for mucosal vaccine. To elucidate the possibility of developing a nasal vaccine against nontypeable Haemophilus influenzae (NTHI) and to investigate mucosal immune responses in the middle ear, mice wer...

Complexes of polyphosphate esters with antibiotics were developed in Lviv Polytechnic National University together scientists Institute Animal Biology NAAS to reduce the negative impact on animal body. The conducted experiments allow assessing effect antibiotics, and complexes body laboratory animals based biochemical markers hepato- nephrotoxicity. administered average daily therapeutic doses....

We show that the 4-coloring problem can be solved in polynomial time for graphs with no induced 5-cycle C5 and no induced 6-vertex path P6.

This paper strengthens the excluded-minor characterization of GF(4)-representable matroids. In particular, it is shown that there are only finitely many 3-connected matroids that are not GF(4)-representable and that have no U2, 6 -, U4, 6 -, P6 -, F & 7 -, or (F & 7 )*-minors. Explicitly, these matroids are all minors of S(5, 6, 12) with rank and corank at least 4, and P"8 , the matroid that ca...

We prove that there are 24 4-critical P6-free graphs, and give the complete list. We remark that, if H is connected and not a subgraph of P6, there are infinitely many 4-critical H-free graphs. Our result answers questions of Golovach et al. and Seymour.

On the basis of mouse I-Ab-binding motifs, two sequences of the murine apolipoprotein B-100 (mApoB-100), mApoB-1003501-3515 (designated P3) and mApoB-100978-992 (designated P6), were found to be immunogenic. In this report, we show that P6 is also atherogenic. Immunization of Apoe-/- mice fed a high-fat diet (HFD) with P6 resulted in enhanced development of aortic atheroma as compared to contro...

The reactivities of 5,5’-Dithiobis (2-nitrobenzoate) with the sulphydryl groups of major haemoglobin of duck (Anas platyrhinchos) have been carried out in the presence of inositol hexakisphosphate, inositol-P6. The time course of the reaction is biphasic. The addition of inositol-P6 changed the pH dependence profile of the apparent second-order rate constant of both oxyand carbonmonoxyhaemoglob...

The proteolytic processing of human immunodeficiency virus (HIV) particles mediated by the viral pol-encoded protease (PR) is essential for viral infectivity. The pol coding sequence partially overlaps with the gag coding sequence and is translated as a Gag-Pol polyprotein precursor. Within Gag-Pol, the C-terminal p6(gag) domain is replaced by a transframe peptide referred to as p6*, which sepa...