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Let G be a graph, u be a vertex of G, and B(u)(or BG(u)) be the set of u with all its neighbors in G. A sequence (B1, B2, ..., Bn) of subsets of an n-set S is a neighborhood sequence if there exists a graph G with a vertex set S and a permutation (v1, v2, ..., vn) of S such that B(vi) = Bi for i = 1, 2, ..., n. Define Aut(B1, B2, ..., Bn) as the set {f : f is a permutation of V (G) and (f(B1), ...

Glomerular development proceeds through the spatially ordered and sequential recruitment, proliferation, assembly, and differentiation of endothelial, mesangial, and epithelial progenitors. The molecular determinants of cell-cell recognition and targeting in this process have yet to be defined. The Eph/ephrin family of membrane receptors and counter-receptors are critical participants of develo...

A few reports were found on the riboflavin (B2) in the eye tissues in various species (1-3). Flavin compound in the eye of Rana nigromaculata concentrates in the choroid, iris, ciliary body and is not present in other parts. The amount and distribution of flavin compound in the eye varies considerably in different species of frogs (4). The presence of B2 in the lens of haddock (Gadus aeglefinus...

Two B-type cyclins, B1 and B2, have been identified in mammals. Proliferating cells express both cyclins, which bind to and activate p34(cdc2). To test whether the two B-type cyclins have distinct roles, we generated lines of transgenic mice, one lacking cyclin B1 and the other lacking cyclin B2. Cyclin B1 proved to be an essential gene; no homozygous B1-null pups were born. In contrast, nulliz...

The relation between B2 cells and commensal microbes during atherosclerosis remains largely unexplored. Here we show that under hyperlipidemic conditions intestinal microbiota resulted in recruitment and ectopic activation of B2 cells in perivascular adipose tissue, followed by an increase in circulating IgG, promoting disease development. In contrast, disruption of the intestinal microbiota by...

A Sidon set is a set A of integers such that no integer has two essentially distinct representations as the sum of two elements of A. More generally, for every positive integer g, a B2[g]-set is a set A of integers such that no integer has more than g essentially distinct representations as the sum of two elements of A. It is proved that almost all small sumsets of {1, 2, . . . , n} are B2[g]-s...

Betanodaviruses are small positive-sense bipartite RNA viruses that infect a wide variety of fish species and are notorious for causing lethal outbreaks in juvenile fish hatcheries worldwide. The function of a small nonstructural protein, B2, encoded by the subgenomic RNA3 of betanodaviruses, has remained obscure. Greasy grouper nervous necrosis virus, a betanodavirus model, was used to develop...

Epilepsy is a chronic neurological disorder characterized by recurrent seizures. However, approximately one-third of epilepsy patients still suffer from uncontrolled seizures. Effective treatments for epilepsy are yet to be developed. N (6)-(3-methoxyl-4-hydroxybenzyl) adenine riboside (B2) is a N(6)-substitued adenosine analog. Here we describe an investigation of the effects and mechanisms of...