Genetic improvement of wheat for heat tolerance is the main breeding objective in Sudan as it principal limiting factor production. To this end, availability genetic diversity key success. diversities and genome-wide association studies were conducted to parse complex composition yield-related traits 250 bread genotypes which selected from ICARDA’s advanced materials. The evaluated under stress...

Stable annulated diaminocarbene ligands 7,9-bis(2,4,6-trimethylphenyl)-6b,9a-dihydroace naphtha[1,2-d]imidazolin-2-ylidene and 7,9-bis(2,6-diisopropylphenyl)-6b,9a-dihydroacenaphtho[1,2-d]imidazolin-2-ylidene; designated as (BIAN-SIMes, 5a,) and (BIAN-SIPr, 5b), respectively, have been prepared. The base dependent decomposition of imidazolinium salts via ring opening at the backbone was also ob...

Human herpesvirus-6B (HHV-6B), a causative agent of exanthem subitum, infects human adult T cell leukemia (ATL) cell lines. We established a persistent HHV-6B infection in an ATL cell line, TaY, in the presence of 20 units/ml interleukin-2 (IL-2). The HHV-6B infected culture proliferated with a constant ratio of infected (1%) to the uninfected (99%) cells. When the IL-2 concentration was reduce...

Abstract Human herpes virus 6 (HHV-6) is a ubiquitous and most common pathogen that affects humans. 6B (HHV-6B) wide spread human herpesvirus infects people when they are children, establishes latent infections in the central nervous system (CNS), especially hippocampus amygdala, induces neurologic diseases. HHV-6 can establish infection be reactivated by various stimuli. Recently, viral genomi...

Streptococcus pneumoniae expressing serogroup 6 capsules frequently causes pneumococcal infections and the evolutionary origins of the serogroup 6 strains have been extensively studied. However, these studies were performed when serogroup 6 had only two known members (serotypes 6A and 6B) and before the two new members (serotypes 6C and 6D) expressing wciN(β) were found. We have therefore reinv...

BACKGROUND A putative Streptococcus pneumoniae serotype, 6D, resulting from the introduction of wciN(beta) into serotype 6B has been proposed. METHODS We studied 98 unique serogroup 6 isolates from Fijian children, two-thirds of whom had received at least 1 dose of 7-valent pneumococcal conjugate vaccine, and 51 invasive isolates from Australian children. We used a polymerase chain reaction (...

Here, we demonstrate that human herpesvirus 6B (HHV-6B) infection upregulates the tumour suppressor p53 and induces phosphorylation of p53 at Ser392. Interestingly, phosphorylation at the equivalent site has previously been shown to correlate with p53 tumour suppression in murine models. Although the signalling pathways leading to Ser392 phosphorylation are poorly understood, they seem to inclu...

Prevalence of serotype 6B penicillin (PEN)-nonsusceptible Streptococcus pneumoniae significantly increased from 15.8% (1993-1997) to 67.3% (1998-2002) (p<0.001) in Argentina. Serogroup 6 ranks fourth among different capsular types within invasive isolates from Argentinean patients <6 years of age. To evaluate whether the increase in PEN resistance in serotype 6B pneumococci was due to the disse...

BACKGROUND We investigated the immune response to serogroup 6 with the opsonophagocytic killing assay (OPKA) in children aged 12-23 months of age after immunization with the 7-valent pneumococcal conjugate vaccine (PCV7) containing serotype 6B. METHODS Blood samples were obtained from 59 children who had blood sampling for medical examination. Immunization status against PCV7 was confirmed by...