The aim of the study was to determine the mycobiota and natural levels of mycotoxins such as aflatoxin B1 (AFB1), ochratoxin A (OTA), fumonisin B1 (FB1), and deoxynivalenol (DON) present in brewers grains pre- and poststored intended for bovine intensive rearing. Poststored (80%) samples had counts higher than 1 × 10(4) colony-forming units (CFU/g). Cladosporium spp. and Aspergillus spp. were i...

Heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 is an RNA binding protein that is required for maturation of mRNA precursor. Tockman et al. previously reported that hnRNP A2/B1 with a M(r) of 31,000 is overexpressed from the early clinical stage of human lung cancer (M. S. Tockman et al., J. Clin. Oncol., 6: 1685-1693, 1988). However, when hnRNP A2/B1 mRNA and hnRNP B1 mRNA were separatel...

Baker et al. . 514,381 Lee et al. 546,167 Brooks et al. Beller et al. Okamoto et al. Breikss et al. ... ... 558.338 Sullivan et al. . ... 570, 183 Adams et al. .............. 544,123 526,115 5,858,907 A * 1/1999 Wang et al. ................ 502,213 5,874,606 A * 2/1999 Huang et al. ............... 558,411 5,922,898 A 7, 1999 Miller et al. 6,075,171 A * 6/2000 Sullivan et al. ............. 57Of ...

Cyclin B1 is a key molecule for G2-M-phase transition during the cell cycle and is overexpressed in various tumor types. However, the expression status of cyclin B1 in lung cancer and its clinical significance remain unknown. We used immunohistochemistry studies to examine the expression of cyclin B1 in 77 non-small cell lung cancer specimens from patients with histological stage I disease. All...

OBJECTIVE The abundance of HDL particles correlates inversely with the incidence of coronary heart disease. The human scavenger receptor B1 (hSR-B1/CLA-1) is a receptor for HDL. Expression of hSR-B1/CLA-1 mRNA and protein in human platelets was determined using reverse transcriptase-polymerase chain reaction and Western blot, respectively. Presence of the protein on the surface of platelets was...

Siglec-G is an inhibitory receptor on B1 cells. Siglec-G-deficient mice show a large B1 cell expansion, owing to higher BCR-induced Ca(2+) signaling and enhanced cellular survival. It was unknown why Siglec-G shows a B1 cell-restricted inhibitory function. With a new mAb we could show a comparable Siglec-G expression on B1 cells and conventional B2 cells. However, Siglec-G has a different ligan...

Cyclin B1 is a key molecule for G2-M-phase transition during the cell cycle and is overexpressed in various tumor types. However, the expression status of cyclin B1 in lung cancer and its clinical significance remain unknown. We used immunohistochemistry studies to examine the expression of cyclin B1 in 77 non-small cell lung cancer specimens from patients with histological stage I disease. All...

The absolute stereochemical description of fumonisin B1 (FB1) and presumably of its congeners is now secure. In this article I summarize studies leading to this conclusion and outline the biosynthetic and synthetic studies of FB1.

Somenewtriethylammoniumsalts,namelytriethylammonium4-(cyclohexyl-amino)-4-oxobut-2-enoate(B1),triethylammonium5-(cyclohexylamino)-5-oxopentanoate(B2),triethylammonium4-(cyclohexylamino)-4-oxobutanoate(B3)weresynthesizedasacorrosioninhibitorformildsteel.Thesesaltscouldtestinonemolaritysulfuricacidatroomtemperaturefor24hoursbyusingweightoflosingmethod.Theresultsrevealedthattheefficiencyofinhibiti...

Hsp90α (heat shock protein 90α), one of the important molecular chaperones in cancer cell signal transduction, has been a new candidate target for cancer therapy. Cyclin B1, the client protein of Hsp90α, plays a key role as a mitotic cyclin in the G2-M phase transition during the cell cycle progression. However, the relationship between the level of HSP90α and cyclin B1, the location of Hsp90α ...