PURPOSE The majority of circulating human γδT lymphocytes are of the Vγ9Vδ2 lineage, and have T-cell receptor (TCR) specificity for nonpeptide phosphoantigens. Previous attempts to stimulate and expand these cells have therefore focused on stimulation using ligands of the Vγ9Vδ2 receptor, whereas relatively little is known about variant blood γδT subsets and their potential role in cancer immun...

To the Editor: In a recent paper by Hu et al. [1], a one-locus, three-allele system is proposed for the three forms ofhuman oculocutaneous albinism. In table 3 of their report, tyrosinase-positive (ty-pos) and tyrosinase-negative (ty-neg) albinism are shown to be, respectively, the heterozygous and homozygous states of the t allele. Previous work by others, as well as their own data, would seem...

In this article I consider some recent objections raised against the syntactic treatment of negation in English multiclausal structures, particular what has been called NEG-raising. argue that based on pronominalisation and ellipsis presented literature do pose a problem for accounts mechanisms so-called NOT-transportation rely rule leftwards movement, as is customary generative grammar. Howeve...

The current study tested the emotional reactivity of smokers with and without histories of major depression (MDD Hx) and trauma exposure (TE). Four counterbalanced conditions nested negative (e.g., dysphoric) or neutral mood inductions with in vivo versus control smoking paraphernalia cues (Neutral+Control; Neutral+Cigarette; Neg+Control; Neg+Cigarette). Mixed model analysis of covariance (ANCO...

In this paper, I give an analysis of neg-raising inferences as scalar implicatures. The main motivation for this account as opposed to a presupposition-based approach (Bartsch 1973 and Gajewski 2005, 2007) comes from the differences between presuppositions and neg-raising inferences, noticed by Gajewski (2005, 2007) and Homer (2012). In response to this issue, Gajewski (2007) argues that neg-ra...

This perspective focuses on illustrating the underappreciated connections between reactive carbonyl species (RCS), initial binding in the nonenzymatic glycation (NEG) process, and nonenzymatic covalent protein modification (here termed NECPM). While glucose is the central species involved in NEG, recent studies indicate that the initially-bound glucose species in the NEG of human hemoglobin (Hb...