Numerical investigations have been made of responses of a Hodgkin-Huxley (HH) neuron to spike-train inputs whose interspike interval (ISI) is modulated by deterministic, semi-deterministic (chaotic), and stochastic signals. As deterministic one, we adopt inputs with the time-independent ISI and with time-dependent ISI modulated by sinusoidal signal. The Rössler and Lorentz models are adopted fo...

OBJECTIVES Use of a local calibrator has been recommended for standardization of the international normalized ratio (INR) and international sensitivity index (ISI). We investigated the performance of two commercial local calibrators for warfarin monitoring and determined the significance of liver-specific INR. METHODS ISI values were determined using the World Health Organization (WHO) method...

OBJECTIVE Despite numerous examinations of factors affecting P300 speller performance, the impact of stimulus presentation parameters remains incompletely understood. This study examines the effects of four distinct stimulus presentation parameters (stimulus-off time [ISI(∗)], interstimulus interval [ISI], flash duration, and flash-duration:ISI ratio) on the accuracy and efficiency of the P300 ...

Neurons produce action potentials or spikes in response to a wide variety of inputs. Correlations between interspike intervals are often seen in data from single neurons, and are due to a combination of intrinsic mechanisms and the temporal properties of the input stimulus. Here we review recent progress in our understanding of how intrinsic correlations arise in simple biophysically justified ...

A moving random-dot stimulus was presented in two sequential frames separated by an interstimulus interval (ISI) during which the field was spatially uniform with luminance equal to either the average luminance of the stimulus field (grey) or that of the black dots (black). In Experiment 1, black ISIs did not affect perception of motion direction but grey ISIs produced motion in the direction o...