Abreu-Martin, Maria T., Andrew A. Palladino, Mary Faris, Nelson M. Carramanzana, André E. Nel, and Stephan R. Targan. Fas activates the JNK pathway in human colonic epithelial cells: lack of a direct role in apoptosis. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G599–G605, 1999.—Fas is expressed constitutively by colonic epithelial cells, and its ligand is expressed by intraepithelia...

Kriston, Tünde, Rocco C. Venuto, Christine Baylis, and György Losonczy. Hemodynamic and renal effects of U-46619, a TXA2/PGH2 analog, in late-pregnant rats. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R831–R837, 1999.—The vasoconstrictor effects of pressor agents are attenuated during pregnancy. Thromboxane A2 (TXA2) is produced in great quantities during hypertension in pre...

Huang, Qin-Heng, Victor J. Hruby, and Jeffrey B. Tatro. Role of central melanocortins in endotoxin-induced anorexia. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R864–R871, 1999.—Inflammation and microbial infection produce symptoms, including fever, anorexia, and hypoactivity, that are thought to be mediated by endogenous proinflammatory cytokines. Melanocortins are known to...

Taylor, Ryan P., M. Brennan Harris, and Joseph W. Starnes. Acute exercise can improve cardioprotection without increasing heat shock protein content. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H1098–H1102, 1999.—The aim of this study was to determine the effects of acute bouts of exercise on myocardial recovery after ischemia and heat shock protein expression. Adult female Sprague-Dawley ra...

O’Connor, Timothy P., and Jared Diamond. Ontogeny of intestinal safety factors: lactase capacities and lactose loads. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R753–R765, 1999.—We measured intestinal safety factors (ratio of a physiological capacity to the load on it) for lactose digestion in developing rat pups. Specifically, we assessed the quantitative relationships bet...

M. J. P. LENCZOWSKI,1 R.-M. BLUTHÉ,2 J. ROTH,3 G. S. REES,4 D. A. RUSHFORTH,5 A.-M. VAN DAM,1 F. J. H. TILDERS,1 R. DANTZER,2 N. J. ROTHWELL,5 AND G. N. LUHESHI5 1Department of Pharmacology, Faculty of Medicine, Research Institute Neurosciences Vrije Universiteit, Graduate School Neurosciences Amsterdam, 1081 BT Amsterdam, The Netherlands; 2Institut François Magendie, Institut National de la Re...

JAMES R. GUM, JR.,1,2 JAMES W. HICKS,3 ANNE-MARIE GILLESPIE,4 ELAINE J. CARLSON,4 LAZLO KÖMÜVES,5 SATYAJIT KARNIK,1 JOE C. HONG,3 CHARLES J. EPSTEIN,4 AND YOUNG S. KIM1,3 1Gastrointestinal Research Laboratory, Department of Veterans Affairs Medical Center, San Francisco 94121; and Departments of 2Anatomy, 3Medicine, 4Pediatrics, and 5Dermatology, University of California at San Francisco, Calif...

Landesberg, Amir, and Samuel Sideman. Regulation of energy consumption in cardiac muscle: analysis of isometric contractions. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H998–H1011, 1999.—The well-known linear relationship between oxygen consumption and force-length area or the force-time integral is analyzed here for isometric contractions. The analysis, which is based on a biochemical mode...

Alexander, EdwardA., Dennis Brown, Theodora Shih, Mary McKee, and John H. Schwartz. Effect of acidification on the location of H1-ATPase in cultured inner medullary collecting duct cells. Am. J. Physiol. 276 (Cell Physiol. 45): C758–C763, 1999.—In previous studies, our laboratory has utilized a cell line derived from the rat inner medullary collecting duct (IMCD) as a model system for mammalian...

Darimont, Christian, Nathalie Gradoux, and Alain De Pover. Epidermal growth factor regulates fatty acid uptake and metabolism in Caco-2 cells. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G606–G612, 1999.—Epidermal growth factor (EGF) has been reported to stimulate carbohydrate, amino acid, and electrolyte transport in the small intestine, but its effects on lipid transport are poorly...