This paper presents an experimental evaluation of our scenario-based multithreading for real-time object-oriented models by the use of a case study of a Private Branch eXchange (PBX) system. The PBX system was taken from the industry and exhibits a number of characteristics found in real-world applications such as a highly reconfigurable dynamic structure and a typical layered architecture. The...

This paper studies the effects of cell residence times on wireless private branch exchange (WPBX) systems. In a WPBX, several base stations are connected to a PBX, and the PBX is connected to the Public Switched Telephone Network. It is important to determine the external line capacity and the radio channel capacities of a WPBX to optimize its system performance. Our previous study utilized an ...

Nowadays, many projects are carried out in a collaboration of people or groups from different institutions and/or enterprises. Such a virtual organization is characterized by high communication needs but does not operate in one single environment. MetaVoIP eases the communication as it automatically combines contact information from different PBXs and provides it to all partners. For a given vi...

The homeobox factor PDX-1 is a key regulator of pancreatic morphogenesis and glucose homeostasis; targeted disruption of the PDX-1 gene leads to pancreatic agenesis in pdx-1(-/-) homozygotes. Pdx-1 heterozygotes develop normally, but they display glucose intolerance in adulthood. Like certain other homeobox proteins, PDX-1 contains a consensus FPWMK motif that promotes heterodimer formation wit...

The second and third amino acid residues of the N-terminal arm of most Hox protein homeodomains are basic (lysine or arginine), whereas they are asparagine and alanine, respectively, in the Hoxa1 homeodomain. Previous reports pinpointed these residues as specificity determinants in the function of Hoxa1 when it is acting as a monomer. However, in vitro data supported that these residues do not ...

Suppression subtractive hybridization performed on Down syndrome (DS) fetal brains revealed a differentially expressed gene, FABP7, mapped to 6q22-23. FABP7 overexpression in DS brains was verified by real-time PCR (1.63-fold). To elucidate the molecular basis of FABP7 overexpression and establish the relationship with chromosome 21 trisomy, the FABP7 promoter was cloned by genomic inverse PCR....

Terminal differentiation programs in the nervous system are encoded by cis-regulatory elements that control the expression of terminal features of individual neuron types. We decoded the regulatory information that controls the expression of five enzymes and transporters that define the terminal identity of all eight dopaminergic neurons in the nervous system of the Caenorhabditis elegans herma...