We report a methodology for the isolation of peroxisome membranes from the yeast Candida tropicalis pK233 grown on oleic acid, and the characterization of the polypeptide and lipid compositions of these membranes. Peroxisomes purified in either sucrose or Nycodenz gradients are treated with Tris-HCl (pH 8.5) and then with sodium carbonate (pH 11.5) to yield a final peroxisome membrane preparati...

BACKGROUND Mutations in the peripheral myelin protein 22 (PMP-22) gene are the most common cause of Charcot-Marie-Tooth neuropathy and may rarely occur in combination with other neurogenetic diseases. OBJECTIVE To characterize 3 families having a mutation in PMP-22 in addition to another neurogenetic disease mutation. DESIGN Clinical, electrophysiologic, and genetic evaluations were made of...

Light responses (ReP) and pre-stimulus membrane potential (PMP) and conductance of photoreceptors of Astacus leptodactylus and Limulus polyphemus (lateral eye) were recorded and changes were observed when the photoreceptor was depolarized by the action of external ouabain of high potassium concentration application. 1 mM/1 ouabain application causes a transient increase of PMP and ReP in Limulu...

BACKGROUND Pseudomyxoma peritonei (PMP) is an uncommon but lethal variant of adenocarcinoma. Many recent case series have reported improved survival with the combination of cytoreductive surgery and intraperitoneal chemotherapy (IPEC) in treating PMP. The aim of this study was to analyze the published studies for improved survival with this treatment strategy. METHODS Data from all studies us...

Overexpression of folate receptor alpha (FRα) and high telomerase activity are considered to be the characteristics of ovarian cancers. In this study, we developed FRα-targeted lipoplexes loaded with an hTERT promoter-regulated plasmid that encodes a matrix protein (MP) of the vesicular stomatitis virus, F-LP/pMP(2.5), for application in ovarian cancer treatment. We first characterized the phar...

The brain is capable of elaborating and executing different stages of information processing. However, exactly how these stages are processed in the brain remains largely unknown. This study aimed to analyze the possible correlation between early and late stages of information processing by assessing the latency to, and amplitude of, early and late event-related potential (ERP) components, incl...

A series of fruitful results were achieved in the course of our study on the fabrication of superconductor YBCO single domain by Powder Melting Process (PMP). First, by the high temperature Faraday Balance, we revealed the dynamic phase transition in the growth of YBCO single domain in PMP process, which is an original research work in this field. The clear phase transition results build a fund...

This paper addresses the problem of motion planning in dynamic environments. As dynamic environments impose a real-time constraint, the planner has a limited time only to compute a motion. Given the intrinsic complexity of motion planning, computing a complete motion to the goal within the time available is, in many real-life situations, impossible to achieve. Partial Motion Planning (PMP) is t...

The Protein Model Portal (PMP) has been developed to foster effective use of 3D molecular models in biomedical research by providing convenient and comprehensive access to structural information for proteins. Both experimental structures and theoretical models for a given protein can be searched simultaneously and analyzed for structural variability. By providing a comprehensive view on structu...

While evidence exists for an association between people management practices (PMP), firm characteristics and lean manufacturing (LMP), there is limited research focusing on different sized firms. What not understood (1) what PMP bundles are chosen by firms which adopt LMP, (2) play a role in explaining these choices. The empirical based archival data sourced from the world dataset comprising of...